Evidence map›Paper›PMID 34728469›Full record

ReviewCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2022

Alcohol and Cancer: Existing Knowledge and Evidence Gaps across the Cancer Continuum.

Susan M Gapstur, Elisa V Bandera, David H Jernigan, Noelle K LoConte, Brian G Southwell, Vasilis Vasiliou, Abenaa M Brewster, Timothy S Naimi, Courtney L Scherr, Kevin D Shield

Abstract readReview
In one paragraph

Review in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Therapeutics for Alcohol-Associated Liver Disease.Annual review of pharmacology and toxicology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Mechanistic Insights into Tumorigenesis from Serum Proteins.medRxiv : the preprint server for health sciences · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Susan M GapsturEpidemiology Consultant, Tiffin, Iowa. sueg1050@gmail.com.
Elisa V BanderaRutgers Cancer Institute of New Jersey, Cancer Epidemiology and Health Outcomes, New Brunswick, New Jersey.ORCID 0000-0002-8789-2755
David H JerniganBoston University School of Public Health, Health Law, Policy and Management, Boston, Massachusetts.
Noelle K LoConteUniversity of Wisconsin School of Medicine and Public Health, Madison Wisconsin.ORCID 0000-0002-3883-4153
Brian G SouthwellRTI International, Center for Communication Science, Research Triangle Park, North Carolina.ORCID 0000-0001-5091-8782
Vasilis VasiliouYale University School of Public Health, New Haven, Connecticut.
Abenaa M BrewsterThe University of Texas MD Anderson Cancer Center, Houston, Texas.
Timothy S NaimiUnivesity of Victoria, Canadian Institute for Substance Use Research, Victoria, British Columbia, Canada.
Courtney L ScherrNorthwestern University School of Communication, Evanston, Illinois.
Kevin D ShieldCentre for Addiction and Mental Health, Toronto, Ontario, Canada.ORCID 0000-0003-1871-8849

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863NCI NIH HHS 75N91020P00609
6 · The paper itself

Abstract

Alcoholic beverages are carcinogenic to humans. Globally, an estimated 4.1% of new cancer cases in 2020 were attributable to alcoholic beverages. However, the full cancer burden due to alcohol is uncertain because for many cancer (sub)types, associations remain inconclusive. Additionally, associations of consumption with therapeutic response, disease progression, and long-term cancer outcomes are not fully understood, public awareness of the alcohol-cancer link is low, and the interrelationships of alcohol control regulations and cancer risk are unclear. In December 2020, the U.S. NCI convened a workshop and public webinar that brought together a panel of scientific experts to review what is known about and identify knowledge gaps regarding alcohol and cancer. Examples of gaps identified include: (i) associations of alcohol consumption patterns across the life course with cancer risk; (ii) alcohol's systemic carcinogenic effects; (iii) alcohol's influence on treatment efficacy, patient-reported outcomes, and long-term prognosis; (iv) communication strategies to increase awareness of the alcohol-cancer link; and (v) the impact of alcohol control policies to reduce consumption on cancer incidence and mortality. Interdisciplinary research and implementation efforts are needed to increase relevant knowledge, and to develop effective interventions focused on improving awareness, and reducing harmful consumption to decrease the alcohol-related cancer burden.

Indexed as

Alcoholic BeveragesHarm ReductionHealth BehaviorHumansNeoplasmsRisk Factors

Identifiers

PMID34728469
PMCPMC8755600

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.