Evidence map›Paper›PMID 34728457›Full record

ArticleBMJ open2021

Integrating health services for HIV infection, diabetes and hypertension in sub-Saharan Africa: a cohort study.

Josephine Birungi, Sokoine Kivuyo, Anupam Garrib, Levicatus Mugenyi, Gerald Mutungi, Ivan Namakoola, Janneth Mghamba, Kaushik Ramaiya, Duolao Wang, Sarah Maongezi and 15 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 10 institutions in 4 countries.

Josephine Birungi *MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Sokoine Kivuyo *Muhimbili Medical Research Centre, National Institute for Medical Research Muhimbili Research Centre, Dar Es Salaam, Tanzania.
Anupam Garrib *Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Levicatus MugenyiThe AIDS Support Organization, Kampala, Uganda.
Gerald MutungiNon-Communicable Diseases Control Programme, Ministry of Health, Kampala, Uganda.
Ivan NamakoolaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Janneth MghambaMinistry of Health, Community Development, Gender, Elderly and Children, Dodoma, Tanzania.
Kaushik RamaiyaShree Hindu Mandal Hospital, Dar es Salaam, Tanzania.
Duolao WangDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0003-2788-2464
Sarah MaongeziMinistry of Health, Community Development, Gender, Elderly and Children, Dodoma, Tanzania.
Joshua MusinguziAIDS Control Programme, Ministry of Health, Kampala, Uganda.
Kenneth MugishaThe AIDS Support Organization, Kampala, Uganda.
Bernard M EtukoitThe AIDS Support Organization, Kampala, Uganda.
Ayoub KakandeMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Louis Wihelmus NiessenDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Joseph OkebeDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Tinevimbo ShiriDepartment of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.
Shimwela MeshackAmana Regional Referral Hospital, Dar es Salaam, Tanzania.
Janet LutaleMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Geoff GillLiverpool School of Tropical Medicine, Liverpool, UK.
Nelson SewankamboMakerere University College of Health Sciences, Kampala, Uganda.
Peter G SmithMRC International Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, London, UK.
Moffat J NyirendaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Sayoki Godfrey Mfinanga *Muhimbili Medical Research Centre, National Institute for Medical Research Muhimbili Research Centre, Dar Es Salaam, Tanzania.ORCID 0000-0001-9067-2684
Shabbar Jaffar *Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK shabbar.jaffar@lstmed.ac.uk.ORCID 0000-0002-9615-1588
Liverpool School of Tropical Medicine · GBThe AIDS Support Organization · UGLondon School of Hygiene & Tropical Medicine · GBMinistry of Health · UGMinistry of Health, Community Development, Gender, Elderly and Children · TZUganda Virus Research Institute · UGAga Khan Hospital Dar es Salaam · TZMakerere University · UGMuhimbili University of Health and Allied Sciences · TZNational Institute for Medical Research · TZ

Funding

Medical Research Council MR/R010161/1
6 · The paper itself

Abstract

backgroundHIV, diabetes and hypertension have a high disease burden in sub-Saharan Africa. Healthcare is organised in separate clinics, which may be inefficient. In a cohort study, we evaluated integrated management of these conditions from a single chronic care clinic.

objectivesTo determined the feasibility and acceptability of integrated management of chronic conditions in terms of retention in care and clinical indicators. DESIGN AND

settingProspective cohort study comprising patients attending 10 health facilities offering primary care in Dar es Salaam and Kampala.

interventionClinics within health facilities were set up to provide integrated care. Patients with either HIV, diabetes or hypertension had the same waiting areas, the same pharmacy, were seen by the same clinical staff, had similar provision of adherence counselling and tracking if they failed to attend appointments. PRIMARY OUTCOME MEASURES: Retention in care, plasma viral load.

findingsBetween 5 August 2018 and 21 May 2019, 2640 patients were screened of whom 2273 (86%) were enrolled into integrated care (832 with HIV infection, 313 with diabetes, 546 with hypertension and 582 with multiple conditions). They were followed up to 30 January 2020. Overall, 1615 (71.1%)/2273 were female and 1689 (74.5%)/2266 had been in care for 6 months or more. The proportions of people retained in care were 686/832 (82.5%, 95% CI: 79.9% to 85.1%) among those with HIV infection, 266/313 (85.0%, 95% CI: 81.1% to 89.0%) among those with diabetes, 430/546 (78.8%, 95% CI: 75.4% to 82.3%) among those with hypertension and 529/582 (90.9%, 95% CI: 88.6 to 93.3) among those with multimorbidity. Among those with HIV infection, the proportion with plasma viral load <100 copies/mL was 423(88.5%)/478.

conclusionIntegrated management of chronic diseases is a feasible strategy for the control of HIV, diabetes and hypertension in Africa and needs evaluation in a comparative study.

Indexed as

Diabetes MellitusHIV InfectionsHypertensionAmbulatory Care FacilitiesCohort StudiesFemaleHealth ServicesHumansProspective StudiesTanzaniaUgandadiabetes & endocrinologyhealth policyHIV & AIDShypertension

Identifiers

PMID34728457
PMCPMC8565555
OpenAlexW3208830650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.