Evidence map›Paper›PMID 34728285›Full record

ArticleJournal of affective disorders2022

The interplay between acute post-traumatic stress, depressive and anxiety symptoms on healthcare workers functioning during the COVID-19 emergency: A multicenter study comparing regions with increasing pandemic incidence.

Claudia Carmassi, Valerio Dell'Oste, Eric Bui, Claudia Foghi, Carlo Antonio Bertelloni, Anna Rita Atti, Rodolfo Buselli, Marco Di Paolo, Arianna Goracci, Paolo Malacarne and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Claudia CarmassiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Valerio Dell'OsteDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy. Electronic address: valerio.delloste@gmail.com.
Eric BuiDepartment of Psychiatry, Caen University and Caen University Hospital, Caen, France.
Claudia FoghiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Carlo Antonio BertelloniDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Anna Rita AttiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Rodolfo BuselliOccupational Health Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Marco Di PaoloDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
Arianna GoracciDepartment of Molecular and Developmental medicine, University of Siena, Siena, Italy.
Paolo MalacarneAnaesthesia and Intensive Care Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Maria Giulia NanniDepartment of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy.
Camilla GesiDepartment of Mental Health and Addiction, ASST Fatebenefratelli-Sacco, Milan, Italy.
Giancarlo CerveriDepartment of Mental Health and Addiction, ASST Lodi, Lodi, Italy.
Liliana Dell'OssoDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
University of Pisa · ITAzienda Ospedaliera Universitaria Pisana · ITUniversity of Siena · ITASST Fatebenefratelli Sacco · ITAziende Socio Sanitarie Territoriale LodiUniversité de Caen Normandie · FRUniversity of Bologna · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare workers (HCWs) deployed to the frontline during the COVID-19 pandemic are at risk for developing mental disorders, with a possible impact on their wellbeing and functioning. The present study aimed at investigating post-traumatic stress symptoms (PTSS), anxiety and depressive symptoms and their relationships with impairment in the functioning impairment among frontline HCWs from three Italian regions differently exposed to the first wave of the COVID-19 emergency: Tuscany (low), Emilia-Romagna (medium) and Lombardy (high).

methods514 frontline HCWs were consecutively enrolled in hospital units devoted to the treatment of COVID-19 patients. They completed the IES-R, PHQ-9 and GAD-7 to assess PTSS, depressive and anxiety symptoms respectively, and the WSAS to investigate functioning impairment.

resultsA total of 23.5% of HCWs reported severe PTSS, 22.4% moderate-severe anxiety symptoms, 19.3% moderate-severe depressive symptoms and 22.8% impairment in global functioning. HCWs from the higher-exposure regions reported significantly higher scores in all instruments than those from lower-exposure regions. In a multiple linear regression model, PTSS, depressive and anxiety symptoms presented a significant positive association with the functioning impairment. Both PTSS and depression resulted to be independently related to functioning impairment. LIMITATIONS: The cross-sectional design and the use of self-report instruments.

conclusionsDepressive and PTSS appear to be the greatest contributors to functioning impairment in HCWs exposed to a massive stressful sanitary event as the COVID-19 pandemic. A more accurate assessment of work-related mental health outcomes in such population could help planning effective prevention strategies and therapeutic interventions.

Indexed as

COVID-19Stress Disorders, Post-TraumaticAnxietyCross-Sectional StudiesDepressionHealth PersonnelHumansIncidencePandemicsSARS-CoV-2AnxietyCoronavirusDepressionEmergency DepartmentsFunctional assessmentPost-traumatic stress disorder

Identifiers

PMID34728285
PMCPMC8556686
OpenAlexW3208024520

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.