Evidence map›Paper›PMID 34728192›Full record

Observational studyArchives of physical medicine and rehabilitation2022

Failure to Compensate: Patients With Nerve Injury Use Their Injured Dominant Hand, Even When Their Nondominant Is More Dexterous.

Benjamin A Philip, Madeline R Thompson, Nathan A Baune, Maureen Hyde, Susan E Mackinnon

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Archives of physical medicine and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Roles of Handedness and Hemispheric Lateralization: Implications for Rehabilitation of the Central and Peripheral Nervous Systems: A Rapid Review.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2024
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Benjamin A PhilipProgram in Occupational Therapy, Washington University School of Medicine, St Louis, Missouri. Electronic address: bphilip@wustl.edu.
Madeline R ThompsonProgram in Occupational Therapy, Washington University School of Medicine, St Louis, Missouri; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri.
Nathan A BauneProgram in Occupational Therapy, Washington University School of Medicine, St Louis, Missouri.
Maureen HydeProgram in Occupational Therapy, Washington University School of Medicine, St Louis, Missouri.
Susan E MackinnonDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, Missouri.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Interhemispheric Communication and Compensation in Peripheral Nerve InjuryR01NS114046 · NINDS · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2021 to 2025
$2.1M
NCATS NIH HHS UL1 TR000448NINDS NIH HHS R01 NS114046
6 · The paper itself

Abstract

objectiveTo identify how individuals respond to unilateral upper extremity peripheral nerve injury via compensation (increased use of the nondominant hand). We hypothesized that injury to the dominant hand would have a greater effect on hand use (left vs right choices). We also hypothesized that compensation would not depend on current (postinjury) nondominant hand performance because many patients undergo rehabilitation that is not designed to alter hand use.

designObservational survey, single-arm. SETTINGS: Academic research institution and referral center.

participantsA total of 48 adults (N=48) with unilateral upper extremity peripheral nerve injury. Another 14 declined participation. Referred sample, including all eligible patients from 16 months at 1 nerve injury clinic and 1 hand therapy clinic.

interventionsNot applicable.

main outcome measuresHand use (% of actions with each hand) via Block Building Task. Dexterity via Jebsen-Taylor Hand Function.

resultsParticipants preferred their dominant hand regardless of whether it was injured: hand usage (dominant/nondominant) did not differ from typical adults, regardless of injured side (P>.07), even though most participants (77%) were more dexterous with their uninjured nondominant hand (mean asymmetry index, -0.16±0.25). The Block Building Task was sensitive to hand dominance (P=2 × 10

conclusionsPatients with peripheral nerve injury with dominant hand injury do not compensate with their unaffected nondominant hand, even if it is more dexterous. For the subset of patients unlikely to recover function with the injured hand, they could benefit from rehabilitation that encourages compensation with the nondominant hand.

Indexed as

Arm InjuriesPeripheral Nerve InjuriesAdultFunctional LateralityHandHumansPsychomotor PerformanceUpper ExtremityFunctional lateralityPeripheral nerve injuriesRehabilitationUpper extremity

Identifiers

PMID34728192
PMCPMC11034713
OpenAlexW3209309809

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.