Evidence map›Paper›PMID 34727878›Full record

ArticleBMC ophthalmology2021

Evaluation of radiation maculopathy after treatment of choroidal melanoma with ruthenium-106 using optical coherence tomography angiography.

Ali Torkashvand, Hamid Riazi-Esfahani, Fariba Ghassemi, Elias Khalili Pour, Babak Masoomian, Mohammad Zarei, Kaveh Fadakar, Mojtaba Arjmand, Fereshteh Tayebi, Leila Ekradi and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Radiation retinopathy: a review.International ophthalmology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Ali TorkashvandEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Hamid Riazi-EsfahaniEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Fariba GhassemiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran. ghasemi_f@sina.tums.ac.ir.
Elias Khalili PourEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Babak MasoomianEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Mohammad ZareiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Kaveh FadakarEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Mojtaba ArjmandEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Fereshteh TayebiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Leila EkradiMachine Vision and Medical Image Processing (MVMIP) Lab, Faculty of Electrical Engineering, K.N. Toosi University of Technology, Tehran, Iran.
Hamid Abrishami MoghaddamMachine Vision and Medical Image Processing (MVMIP) Lab, Faculty of Electrical Engineering, K.N. Toosi University of Technology, Tehran, Iran.
Tahereh MahmoudiDepartment of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences and Research Center for Science and Technology in Medicine, Tehran, Iran.
Reihaneh DaneshmandDepartment of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
Hooshang FaghihiEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Qazvin Square, Tehran, 1336616351, Iran.
Tehran University of Medical Sciences · IRFarabi Hospital · IRK.N.Toosi University of Technology · IRAmirkabir University of Technology · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the impact of brachytherapy on macular microvasculature utilizing optical coherence tomography angiography (OCTA) in treated choroidal melanoma.

methodsIn this retrospective observational case series, we reviewed the recorded data of the patients with unilateral extramacular choroidal melanoma treated with ruthenium - 106 (

resultsThirty-one eyes of 31 patients with the mean age of 51.1 years were recruited. Six eyes had no radiation maculopathy (RM). From 25 eyes with RM, nine eyes (36%) revealed a burnout macular microvasculature with imperceptible vascular details. Twenty-one non-irradiated fellow eyes from the enrolled patients were considered as the control group. Foveal and optic disc radiation dose had the highest value to predict the burnout pattern (ROC, AUC: 0.763, 0.727). Superficial and deep foveal avascular zone (FAZ) were larger in irradiated eyes in comparison to non-irradiated fellow eyes (1629 μm

conclusionThe OCTA is a valuable tool for evaluating RM. Initial subclinical microvascular insult after

Indexed as

Macular DegenerationMelanomaFluorescein AngiographyHumansMiddle AgedRetinal VesselsRetrospective StudiesRuthenium RadioisotopesTomography, Optical CoherenceRuthenium-106Ruthenium RadioisotopesDeep capillary plexusFoveal avascular zone (FAZ)Radiation maculopathyRadiation retinopathyRetina burnoutRuthenium-106Superficial capillary plexus

Identifiers

PMID34727878
PMCPMC8562000
OpenAlexW3154519753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.