Evidence map›Paper›PMID 34727874›Full record

ArticleBMC infectious diseases2021

Seroprevalence of anti-SARS-CoV-2 antibodies and risk factors among healthy blood donors in Luanda, Angola.

Cruz S Sebastião, Manuela Galangue, Celestina Gaston, Rui Van-Dunen, Joltim Quivinja, Emiliana Lunbungululo, Domingos Alfredo, Alberto Sozinho, Alice Teixeira, Eunice Manico and 7 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Cruz S SebastiãoInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Manuela GalangueInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Celestina GastonInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Rui Van-DunenInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Joltim QuivinjaInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Emiliana LunbungululoInstituto Nacional de Sangue, Ministry of Health, Luanda, Angola.
Domingos AlfredoClínica Girassol, Ministry of Health, Luanda, Angola.
Alberto SozinhoInstituto Nacional de Sangue, Ministry of Health, Luanda, Angola.
Alice TeixeiraClínica Girassol, Ministry of Health, Luanda, Angola.
Eunice ManicoInstituto Nacional de Sangue, Ministry of Health, Luanda, Angola.
Deodete MachadoInstituto Nacional de Sangue, Ministry of Health, Luanda, Angola.
António MateusInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Zinga DavidInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Joana PaixãoInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Zoraima NetoInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Jocelyne Neto de VasconcelosInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Joana MoraisInstituto Nacional de Investigação em Saúde (INIS), Luanda, Angola. jfm.morais9@gmail.com.
Ministry of Health · AOAgostinho Neto University · AO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSARS-CoV-2 emerged in China and spread throughout the world due to its rapid transmission. The exposure rate in the healthy population is unknown, mainly in resource-limited countries. Herein, we estimated the seroprevalence of anti-SARS-CoV-2 antibodies and risk factors among blood donors in Luanda, the capital city of Angola.

methodsThis was a retrospective study conducted with 343 blood donors. Chi-square and logistic regression were calculated to predict the independent variable for SARS-CoV-2 infection and deemed significant when p < 0.05.

resultsSeroprevalence of anti-SARS-CoV-2 was 4.7%. Positivity rates varied to age groups (3.5-14.3%), gender (0-5%), area of residence (3.1-.6%), educational level (5.1-10.2%), occupation (4.4-7.7%), and the blood donor category (2.0-5.1%). Past and recent infections were detected in 3.2% and 1.5%, respectively. Blood donors under the age of 20 years (OR: 4.58, p = 0.241) and from non-urbanized areas (OR: 1.86, p = 0.293) presented a high risk related to infection. The infection was higher in blood group A and lower in blood group O. The risk of SARS-CoV-2 infection has increased from January 2020 (OR: 0.03, p = 0.001) to August 2020 (OR: 0.57, p = 0.426).

conclusionsWe provide an estimate of the exposure of healthy blood donors in Luanda. Also, we detected anti-SARS-CoV-2 in January 2020, indicating that the SARS-CoV-2 could have been imported during the first month of 2020. Further studies should be performed to assess the exposure rate in different groups from Angola.

Indexed as

Blood DonorsCOVID-19AdultAngolaAntibodies, ViralCross-Sectional StudiesHumansRetrospective StudiesRisk FactorsSARS-CoV-2Seroepidemiologic StudiesYoung AdultAntibodies, ViralAngolaBlood donorsCOVID-19LuandaSARS-CoV-2Seroprevalence

Identifiers

PMID34727874
PMCPMC8562364
OpenAlexW3208088103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.