Evidence map›Paper›PMID 34727803›Full record

ArticleExpert opinion on drug discovery2022

Using

Camila B P Da Costa, Ana Claudia De Menezes Cruz, Julio Cesar Q Penha, Helena C Castro, Luis E R Da Cunha, Norman A Ratcliffe, Rafael Cisne, Francislene Juliana Martins

Abstract read
In one paragraph

Article in Expert opinion on drug discovery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Marmosets as models of infectious diseases.Frontiers in cellular and infection microbiology · 2024
    Review
  4. Review
  5. Animal models for COVID-19 and tuberculosis.Frontiers in immunology · 2023
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Camila B P Da CostaTechnological Development and Innovation Laboratory of the Industrial Board, Instituto Vital Brazil, Rio De Janeiro, Brazil.ORCID 0000-0002-6926-7956
Ana Claudia De Menezes CruzPrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0002-4520-6884
Julio Cesar Q PenhaPrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0002-5249-9742
Helena C CastroPrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0001-5283-1541
Luis E R Da CunhaTechnological Development and Innovation Laboratory of the Industrial Board, Instituto Vital Brazil, Rio De Janeiro, Brazil.ORCID 0000-0003-1381-0611
Norman A RatcliffePrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0001-8538-0636
Rafael CisnePrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0002-4624-3935
Francislene Juliana MartinsPrograma de Pós-graduação em Ciências e Biotecnologia, IB, UFF, Rio de Janeiro, Brazil.ORCID 0000-0002-6149-8258

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe search for an animal model capable of reproducing the physiopathology of the COVID-19, and also suitable for evaluating the efficacy and safety of new drugs has become a challenge for many researchers. AREAS COVERED: This work reviews the current animal models for EXPERT OPINION: Studies have reported the use of nonhuman primates, ferrets, mice, Syrian hamsters, lagomorphs, mink, and zebrafish in experiments that aimed to understand the course of COVID-19 or test vaccines and other drugs. In contrast, the assays with animal hyperimmune sera have only been used in

Indexed as

COVID-19SARS-CoV-2AnimalsCricetinaeDisease Models, AnimalFerretsHumansMiceZebrafishcoronavirusCOVID-19in vivo modelmammalssafety

Identifiers

PMID34727803
PMCPMC8567288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.