ArticleThe international journal of cardiovascular imaging2022
Improved diastolic dysfunction is associated with higher forward flow and better prognosis in chronic heart failure.
Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Mid-term clinical outcomes and cardiac function in patients receiving cardiac contractility modulation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Echocardiography in the Assessment of Heart Failure Patients.Diagnostics (Basel, Switzerland) · 2024Review
- New perspectives in the echocardiographic hemodynamics multiparametric assessment of patients with heart failure.Heart failure reviews · 2024Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The benefit of repeat assessment of left ventricular (LV) systolic and diastolic function in heart failure (HF) remains uncertain. We assessed the prognostic value of repeat echocardiographic assessment of LV filling pressure (LVFP) and its interaction with cardiac index (CI) in ambulatory patients with chronic HF and reduced ejection fraction (HFrEF). We enrolled 357 patients (age 68 ± 11 years; 22% female) with chronic HFrEF. Patients underwent a clinical and echocardiographic examination at baseline. LVFP as assessed by the 2016 Guidelines and Doppler-derived CI were estimated. After the second echocardiographic examination, patients were followed for a median time of 30 months. The study endpoint included all-cause death and hospitalization for worsening HF. Patients who normalized LVFP or showed persistently normal LVFP at the follow-up examination had a significantly lower mortality rate than those with worsening or persistently raised LVFP (p < 0.0001). After stratification by CI, patients with elevated LVFP and CI < 2.0 l/min/m
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