ArticleRice (New York, N.Y.)2021
The Elite Alleles of OsSPL4 Regulate Grain Size and Increase Grain Yield in Rice.
Article in Rice (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Identification of genes controlling grain size in barley through RNA-seq and weighted gene co-expression network analysis.Functional & integrative genomics · 2026Article
- Dissecting the genetic architecture of silique-related traits in rapeseed (Brassica napus L.) through genome-wide association studies and transcriptome analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- FAD-Linked Oxidoreductase Protein 1 (FLO1) Coordinates Grain Development and Drought Tolerance in Rice.Plants (Basel, Switzerland) · 2026Article
- Zinc Finger Homeobox Transcription Factors OsMIF1 and OsMIF2 Regulate Grain Size and Panicle Development in Rice.Rice (New York, N.Y.) · 2026Article
- Antagonistic effects of selection on alleles associated with seed size and seed dormancy in wheat.Genome biology · 2025Article
- Comparative analyses highlight wheat TaSPL4-D as a promising candidate gene to optimize plant architecture traits in rice.Plant cell reports · 2025Article
- A molecular framework for the GS2-SUG1 module-mediated control of grain size and weight in rice.Nature communications · 2025Article
- Genetic Improvement of rice Grain size Using the CRISPR/Cas9 System.Rice (New York, N.Y.) · 2025Review
- Unleashing the Potential of CRISPR/Cas9 Genome Editing for Yield-Related Traits in Rice.Plants (Basel, Switzerland) · 2024Review
- Profiling of Key Hub Genes Using a Two-State Weighted Gene Co-Expression Network of 'Jao Khao' Rice under Soil Salinity Stress Based on Time-Series Transcriptome Data.International journal of molecular sciences · 2024Article
- QTL mapping and candidate gene mining of seed size and seed weight in castor plant (Ricinus communis L.).BMC plant biology · 2024Article
- OsSPL11 positively regulates grain size by activating the expression of GW5L in rice.Plant cell reports · 2024Article
- The peptidase DA1 cleaves and destabilizes WUSCHEL to control shoot apical meristem size.Nature communications · 2024Article
- Genome-wide identification and expression analysis of the SPL transcription factor family and its response to abiotic stress in Pisum sativum L.BMC genomics · 2024Article
- Differential expression and global analysis of miR156/SQUAMOSA promoter binding-like proteins (SPL) module in oat.Scientific reports · 2024Article
- Rice microRNA156/529-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE7/14/17 modules regulate defenses against bacteria.Plant physiology · 2023Article
- Ectopic Expression of a Maize GeneInternational journal of molecular sciences · 2023Article
- Genetic Localization and Homologous Genes Mining for Barley Grain Size.International journal of molecular sciences · 2023Review
- Integrated multi-locus genome-wide association studies and transcriptome analysis for seed yield and yield-related traits inFrontiers in plant science · 2023Article
- Molecular cloning and functional analysis of Chinese bayberryFrontiers in plant science · 2023Article
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12 authors.
Funding
Abstract
Grain weight and grain number, the two important yield traits, are mainly determined by grain size and panicle architecture in rice. Herein, we report the identification and functional analysis of OsSPL4 in panicle and grain development of rice. Using CRISPR/Cas9 system, two elite alleles of OsSPL4 were obtained, which exhibited an increasing number of grains per panicle and grain size, resulting in increase of rice yield. Cytological analysis showed that OsSPL4 could regulate spikelet development by promoting cell division. The results of RNA-seq and qRT-PCR validations also demonstrated that several MADS-box and cell-cycle genes were up-regulated in the mutation lines. Co-expression network revealed that many yield-related genes were involved in the regulation network of OsSPL4. In addition, OsSPL4 could be cleaved by the osa-miR156 in vivo, and the OsmiR156-OsSPL4 module might regulate the grain size in rice. Further analysis indicated that the large-grain allele of OsSPL4 in indica rice might introgress from aus varieties under artificial selection. Taken together, our findings suggested that OsSPL4 could be as a key regulator of grain size by acting on cell division control and provided a strategy for panicle architecture and grain size modification for yield improvement in rice.
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