Evidence map›Paper›PMID 34727125›Full record

ArticlePloS one2021

Femoral head collapse after hip intra-articular corticosteroid injection: An institutional response to improve practice and increase patient safety.

Brandon J Kelly, Benjamin R Williams, Amy A Gravely, Kersten Schwanz, V Franklin Sechriest

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Non-Biologic Injections in Sports Medicine.Current reviews in musculoskeletal medicine · 2026
    Review
  3. Review
  4. Rapid Osteoarthritis and Femoral Head Collapse: A Case Series.Journal of orthopaedic case reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brandon J KellyDepartment of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America.
Benjamin R WilliamsDepartment of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America.
Amy A GravelyDepartment of Research Service, Veterans Affairs Medical Center, Minneapolis, Minnesota, United States of America.
Kersten SchwanzDepartment of Physical Medicine/Rehabilitation, University of Minnesota, Minneapolis, Minnesota, United States of America.
V Franklin SechriestDepartment of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America.ORCID 0000-0002-3839-2762

Funding

Novel Cilia Trafficking MechanismsR01DK084725 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARGOLIS, BENJAMIN L · 2009 to 2010
$702k
NIDDK NIH HHS R01 DK084725
6 · The paper itself

Abstract

introductionFemoral head collapse (FHC) is a rarely reported complication of hip intra-articular corticosteroid injection (IACSI). Upon observing a high rate of FHC after hip IACSI, we sought to (1) describe how we addressed the problem through a systematic evaluation of clinical data and institutional care practices followed by process improvement efforts; and (2) report our results.

methodsPatients receiving hip IACSI during a 27-month period underwent retrospective review to determine the rate of FHC and to identify associated patient factors or practice shortfalls. Findings led to institution-wide interventions: (1) to improve patient/provider awareness of this association; and (2) to develop/implement practice guidelines. Rates of FHC after hip IACSI and practice patterns among providers before and after intervention were compared.

resultsInitial FHC rate after hip IACSI was 20.4%. Patient-related factors included body mass index (p = 0.025), history of cancer therapy (p = 0.012), Vitamin D level (p = 0.030), and multiple injections (p = 0.004). Volume/dose of injectate and post-injection surveillance methods varied widely. Quality improvement (QI) intervention resulted in fewer treatment referrals (from 851 to 436), fewer repeat injections (mean = 1.61 to 1.37; p = 0.0006), and a 5% lower FHC rate (p = 0.1292). Variation in practice patterns persisted, so a systems-based Clinical Pathway was established. DISCUSSION: When a high rate of FHC after hip IACSI was found to be associated with certain patient and practice factors, introduction of education materials and treatment guidelines decreased number of referrals, number of injections per patient, and FHC rate. In the absence of the systems-based Pathway, the type, dose, and volume of injectate and post-procedure follow-up remained variable.

Indexed as

Adrenal Cortex HormonesFemur HeadAdultAgedFemaleHumansInjections, Intra-ArticularMaleMiddle AgedPatient SafetyQuality ImprovementRetrospective StudiesAdrenal Cortex Hormones

Identifiers

PMID34727125
PMCPMC8562809

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.