SynthesisPLoS neglected tropical diseases2021
The burden of zoonoses in Paraguay: A systematic review.
Synthesis in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The dual burden of animal and human zoonoses: A systematic review.PLoS neglected tropical diseases · 2022Pooled it
- Human infestations with Fasciola hepatica in Austria between 1955 and 2025: data from a low-incidence country.Parasite (Paris, France) · 2026Article
- Spatial heterogeneity of Rift Valley fever burden in Kenya: a 10-year One Health zDALY evaluation.Science in One Health · 2026Article
- Modification ofAnimals : an open access journal from MDPI · 2025Article
- Integrated serological surveillance of communicable diseases in the Paraguayan Chaco, 2019.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Quantifying national burdens of foodborne disease-Four imperatives for global impact.PLOS global public health · 2025Review
- Diversity of Anaplasmataceae Transmitted by Ticks (Ixodidae) and the First Molecular Evidence ofMicroorganisms · 2024Article
- Assessment of the burden of rabies in one health approach control program in Ketapang District Indonesia: Using zDALY.Preventive medicine reports · 2024Article
- Rescue and rehabilitation of maned wolf (Chrysocyon brachyurus) in Paraguay: Case description.Veterinary medicine and science · 2024Article
- Quantifying the neglected: Initial estimation of the global burden and economic impact of human toxocariasis.Current research in parasitology & vector-borne diseases · 2024Article
- The global burden of neglected zoonotic diseases: Current state of evidence.One health (Amsterdam, Netherlands) · 2023Review
- Toxoplasma gondii microneme protein MIC3 induces macrophage TNF-α production and Ly6C expression via TLR11/MyD88 pathway.PLoS neglected tropical diseases · 2023Article
- Respiratory morbidity in human toxocariasis: A scoping review of the literature.Therapeutic advances in infectious diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUnderestimation of zoonoses is exacerbated in low and middle-income countries due mainly to inequalities with serious consequences in healthcare. This is difficult to gauge and reduce the impact of those diseases. Our study focuses on Paraguay, where the livestock industry is one of the major components of the country's economy. Therefore, the rationale of this study was to develop a case study in Paraguay to estimate the dual impact of zoonotic diseases on both the human health and animal health sector and thus determine the societal burden of such diseases. METHODOLOGY/PRINCIPAL
findingsWe conducted a systemic review (including a meta-analysis) to assess the burden of zoonoses in Paraguay, including official reports and grey literature of disease incidence and prevalence. We estimated the Disability Adjusted Life Years (DALYs) and Zoonosis Disability Adjusted Life Years (zDALYs) to measure the difference between the current health status and the desired health situation of animals and the Paraguayan population based on 50 zoonotic diseases suggested by the WHO (World Health Organization), OIE (World Organization for Animal Health) and the National Health in Paraguay. The total DALYs represent 19,384 (95% CI: from 15,805 to 29,733), and zDALYs, 62,178 (95% CI: from 48,696 to 77,188). According to the results, the priority pathogens for DALYs are E. coli, Trypanosoma cruzi, Leishmania spp, and Toxoplasma gondii. When we include the additional animal health burden, the most important pathogens are Brucella spp, E. coli, Trypanosoma cruzi, and Fasciola hepatica for zDALYs. CONCLUSION/SIGNIFICANCE: This is the first study to integrate DALYs and zDALYs with important clues related to the health status of Paraguay. Through DALYs and zDALYs, our perspective becomes more complete because we consider not only human health but also animal health. This is important for setting priorities in disease control, especially in a society where livestock contribute significantly to the economy and to human well-being.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.