Evidence map›Paper›PMID 34726978›Full record

ArticlePublic health reports (Washington, D.C. : 1974)

Characterizing Opioid Overdoses Using Emergency Medical Services Data : A Case Definition Algorithm Enhanced by Machine Learning.

Josie J Sivaraman, Scott K Proescholdbell, David Ezzell, Meghan E Shanahan

Open access · bronzeAbstract read
In one paragraph

Article in Public health reports (Washington, D.C. : 1974). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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  8. Opioid Overdose Surveillance : Improving Data to Inform Action.Public health reports (Washington, D.C. : 1974)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Josie J Sivaraman2331 Department of Epidemiology, University of North Carolina at Chapel Hill, NC, USA.ORCID 0000-0001-7768-4832
Scott K ProescholdbellEpidemiology, Surveillance and Informatics Unit, Injury and Violence Prevention Branch, Chronic Disease and Injury Section, Division of Public Health, North Carolina Department of Health and Human Services, Raleigh, NC, USA.
David Ezzell6800 Division of Health Service Regulation, Office of Emergency Medical Services, North Carolina Department of Health and Human Services, Raleigh, NC, USA.
Meghan E ShanahanInjury Prevention Research Center, University of North Carolina at Chapel Hill, NC, USA.
NC Department of Health and Human Services · USUniversity of North Carolina at Chapel Hill · US

Funding

NCIPC CDC HHS U17 CE002728
6 · The paper itself

Abstract

objectivesTracking nonfatal overdoses in the escalating opioid overdose epidemic is important but challenging. The objective of this study was to create an innovative case definition of opioid overdose in North Carolina emergency medical services (EMS) data, with flexible methodology for application to other states' data.

methodsThis study used de-identified North Carolina EMS encounter data from 2010-2015 for patients aged >12 years to develop a case definition of opioid overdose using an expert knowledge, rule-based algorithm reflecting whether key variables identified drug use/poisoning or overdose or whether the patient received naloxone. We text mined EMS narratives and applied a machine-learning classification tree model to the text to predict cases of opioid overdose. We trained models on the basis of whether the chief concern identified opioid overdose.

resultsUsing a random sample from the data, we found the positive predictive value of this case definition to be 90.0%, as compared with 82.7% using a previously published case definition. Using our case definition, the number of unresponsive opioid overdoses increased from 3412 in 2010 to 7194 in 2015. The corresponding monthly rate increased by a factor of 1.7 from January 2010 (3.0 per 1000 encounters; n = 261 encounters) to December 2015 (5.1 per 1000 encounters; n = 622 encounters). Among EMS responses for unresponsive opioid overdose, the prevalence of naloxone use was 83%.

conclusionsThis study demonstrates the potential for using machine learning in combination with a more traditional substantive knowledge algorithm-based approach to create a case definition for opioid overdose in EMS data.

Indexed as

AlgorithmsAdultEmergency Medical ServicesFemaleHumansMachine LearningMaleMiddle AgedNorth CarolinaOpiate Overdosecase definitionmachine learningnatural language processingopioid overdosesurveillance

Identifiers

PMID34726978
PMCPMC8573782
OpenAlexW3211197061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.