ArticleACS applied materials & interfaces2021
Conducting Polymer-Reinforced Laser-Irradiated Graphene as a Heterostructured 3D Transducer for Flexible Skin Patch Biosensors.
Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Molecularly Imprinted Polymers for Biosensing: From Synthetic Recognition to Integrated Biointerfaces.Micromachines · 2026Review
- Multidimensional and Multifunctional Laser-Induced Graphene (LIG) for Point-of-Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Selectively damping materials for next-generation motion-artifact-free skin-interfaced soft bioelectronics.Materials horizons · 2025Review
- Rational Molecular Design of Aniline-Based Donor-Acceptor Conducting Polymers Enhancing Ionic Molecular Interaction for High-Performance Wearable Bioelectronics.Advanced healthcare materials · 2025Article
- Development, fabrication, and applications of laser-induced graphene-based biosensors in food and dairy sectors.Mikrochimica acta · 2025Review
- Seamless Integration of Laser-Induced Papertronics with Parafilm-Based Microfluidics as a Versatile Paper-Based Electroanalytical Platform.ACS applied materials & interfaces · 2025Article
- Advances in electrical stimulation for wound healing.Frontiers in bioengineering and biotechnology · 2025Review
- Role of wearable electrochemical biosensors in monitoring renal function biomarkers in sweat: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024Review
- Portable glucose sensing analysis based on laser-induced graphene composite electrode.RSC advances · 2024Article
- Smart Multiplex Point-of-Care Platform for Simultaneous Drug Monitoring.ACS applied materials & interfaces · 2023Article
- Skin-interfaced electronics: A promising and intelligent paradigm for personalized healthcare.Biomaterials · 2023Review
- Epidermal Wearable Biosensors for Monitoring Biomarkers of Chronic Disease in Sweat.Biosensors · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flexible skin patch biosensors are promising for the noninvasive determination of physiological parameters in perspiration for fitness and health monitoring. However, various prerequisites need to be met for the development of such biosensors, including the creation of a flexible conductive platform, bending/contact stability, fast electrochemical kinetics, and immobilization of biomolecules. Here, we describe a conducting polymer-reinforced laser-irradiated graphene (LIG) network as a heterostructured three-dimensional (3D) transducer for flexible skin patch biosensors. LIG with a hierarchically interconnected graphene structure is geometrically patterned on polyimide via localized laser irradiation as a flexible conductive platform, which is then reinforced by poly(3,4-ethylenedioxythiophene) (PEDOT) as a conductive binder (PEDOT/LIG) with improved structural/contact stability and electrochemical kinetics. The interconnected pores of the reinforced PEDOT/LIG function as a 3D host matrix for high loading of "artificial" (Prussian blue, PB) and natural enzymes (lactate oxidase, LOx), forming a compact and heterostructured 3D transducer (LOx/PB-PEDOT/LIG) for lactate biosensing with excellent sensitivity (11.83 μA mM
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