Evidence map›Paper›PMID 34726833›Full record

ArticleJournal of applied clinical medical physics2022

Delineation of prostatic calcification using quantitative susceptibility mapping: Spatial accuracy for magnetic resonance-only radiotherapy planning.

Hirohito Kan, Takahiro Tsuchiya, Masato Yamada, Hiroshi Kunitomo, Harumasa Kasai, Yuta Shibamoto

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hirohito KanDepartment of Integrated Health Sciences, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Takahiro TsuchiyaDepartment of Radiology, Nagoya City University Hospital, Nagoya City University, Nagoya, Japan.
Masato YamadaDepartment of Radiology, Nagoya City University Hospital, Nagoya City University, Nagoya, Japan.
Hiroshi KunitomoDepartment of Radiology, Nagoya City University Hospital, Nagoya City University, Nagoya, Japan.
Harumasa KasaiDepartment of Radiology, Nagoya City University Hospital, Nagoya City University, Nagoya, Japan.
Yuta ShibamotoDepartment of Radiology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Nagoya City University Hospital · JPNagoya City University · JPNagoya University · JP

Funding

JSPS KAKENHI 20K16786
6 · The paper itself

Abstract

To investigate the spatial accuracy of delineating prostatic calcifications by quantitative susceptibility mapping (QSM) in comparison with computed tomography (CT), we conducted phantom and human studies. Five differently-sized spherical hydroxyapatites mimicking prostatic calcification (pseudo-calcification) were arranged in the order of their sizes at the center of a plastic container filled with gelatin. This calcification phantom underwent magnetic resonance (MR) imaging, including the multiple spoiled gradient-echo sequences (SPGR) for the QSM and CT as a reference. The volume of each pseudo-calcification and center-to-center distance between the pseudo-calcifications delineated by QSM and CT were measured. In the human study, eight patients with prostate cancer who underwent radiation therapy and had some prostatic calcifications were included. The patients underwent CT and SPGR and modified DIXON sequence for MR-only simulation. The hybrid QSM processing combined with the complex signals in the SPGR and water and fat fraction maps estimated from the modified DIXON sequence were used to reconstruct the pelvic susceptibility map in humans. The threshold of CT numbers was set at 130 HU, while the QSM images were manually segmented in the calcification phantom and human studies. In the phantom study, there was an excellent agreement in the pseudo-calcification volumes between QSM and CT (y = 1.02x - 7.38, R

Indexed as

Prostatic NeoplasmsRadiotherapy, Image-GuidedHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMalePhantoms, ImagingTomography, X-Ray Computedimage-guided radiotherapyMR-only simulationquantitative susceptibility mapping

Identifiers

PMID34726833
PMCPMC8833270
OpenAlexW3208296983

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.