Evidence map›Paper›PMID 34726790›Full record

ArticleJournal of periodontology2022

Access to dental care and blood pressure profiles in adults with high socioeconomic status.

Rita Del Pinto, Annalisa Monaco, Eleonora Ortu, Marta Czesnikiewicz-Guzik, Eva Muñoz Aguilera, Mario Giannoni, Francesco D'Aiuto, Tomasz J Guzik, Claudio Ferri, Davide Pietropaoli

Open access · hybridAbstract read
In one paragraph

Article in Journal of periodontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Rita Del PintoUnit of Internal Medicine and Nephrology - Center for Hypertension and Cardiovascular Prevention - San Salvatore Hospital, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Annalisa MonacoOral DISeases and SYstemic interactions study group (ODISSY group), L'Aquila, Italy.
Eleonora OrtuOral DISeases and SYstemic interactions study group (ODISSY group), L'Aquila, Italy.
Marta Czesnikiewicz-GuzikDepartment of Periodontology and Oral Sciences Research Group, University of Glasgow Dental School, Glasgow, UK.
Eva Muñoz AguileraPeriodontology Unit, UCL Eastman Dental Institute and Hospital, University College London, London, UK.
Mario GiannoniOral DISeases and SYstemic interactions study group (ODISSY group), L'Aquila, Italy.
Francesco D'AiutoPeriodontology Unit, UCL Eastman Dental Institute and Hospital, University College London, London, UK.
Tomasz J GuzikInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Claudio FerriUnit of Internal Medicine and Nephrology - Center for Hypertension and Cardiovascular Prevention - San Salvatore Hospital, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Davide PietropaoliOral DISeases and SYstemic interactions study group (ODISSY group), L'Aquila, Italy.
San Salvatore Hospital · ITUniversity of L'Aquila · ITEastman Dental Hospital · GBJagiellonian University · PLUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular risk at least in part through its effect on blood pressure (BP), possibly mediated by systemic inflammation.

methodsWe first assessed the sociodemographic and clinical characteristics related to last dental visit timing (≤ or >6 months; self-reported) using national representative cross-sectional data. Then, the association of last dental visit timing with clinic BP was selectively investigated in highly educated, high income participants, further matched for residual demographic and clinical confounders using propensity score matching (PSM). The mediating effect of systemic inflammation was formally tested. Machine learning was implemented to investigate the added value of dental visits in predicting high BP over the variables included in the Framingham Hypertension Risk Score among individuals without an established diagnosis of hypertension.

resultsOf 27,725 participants included in the population analysis, 46% attended a dental visit ≤6 months. In the PSM cohort (n = 2350), last dental visit attendance >6 months was consistently associated with 2 mmHg higher systolic BP (P = 0.001) and with 23 to 35% higher odds of high/uncontrolled BP compared with attendance ≤6 months. Inflammation mildly mediated the association. Access to dental care improved the prediction of high BP by 2%.

conclusionsDental care use impacts on BP profiles independent of socioeconomic confounders, possibly through systemic inflammation. Regular dental visits may contribute to preventive medicine.

Indexed as

HypertensionAdultBlood PressureCross-Sectional StudiesDental CareHumansInflammationSocial ClassSocioeconomic Factorsblood pressuredental careinflammationmachine learningoral healthsocioeconomic factors

Identifiers

PMID34726790
PMCPMC9542004
OpenAlexW3211142920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.