Evidence map›Paper›PMID 34726595›Full record

ArticleEmerging infectious diseases2022

Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths.

Fabian Heinrich, Ann Sophie Schröder, Anna-Lina Gerberding, Moritz Gerling, Felicia Langenwalder, Philine Lange, Axel Heinemann, Eric Bibiza-Freiwald, Dominik Sebastian Nörz, Martin Aepfelbacher and 3 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fabian Heinrich
Ann Sophie Schröder
Anna-Lina Gerberding
Moritz Gerling
Felicia Langenwalder
Philine Lange
Axel Heinemann
Eric Bibiza-Freiwald
Dominik Sebastian Nörz
Martin Aepfelbacher
Susanne Pfefferle
Benjamin Ondruschka
Marc Lütgehetmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the infectivity of 128 severe acute respiratory disease coronavirus 2-associated deaths and evaluated predictive values of standard diagnostic procedures. Maintained infectivity (20%) did not correlate with viral RNA loads but correlated well with anti-S antibody levels. Sensitivity >90% for antigen-detecting rapid diagnostic tests supports their usefulness for assessment.

Indexed as

COVID-19SARS-CoV-2AutopsyDiagnostic Tests, RoutineHumansSensitivity and SpecificityViral LoadAg-RDTantigen-detecting rapid diagnostic testcoronaviruscoronavirus disease 2019COVID-19infectivitypostmortemrespiratory infectionsSARS-CoV-2serostatussevere acute respiratory syndrome coronavirus 2viral RNA loadviruseszoonoses

Identifiers

PMID34726595
PMCPMC8714232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.