Evidence map›Paper›PMID 34726486›Full record

ArticlemSystems2021

Analysis of SARS-CoV-2 RNA Persistence across Indoor Surface Materials Reveals Best Practices for Environmental Monitoring Programs.

Rodolfo A Salido, Victor J Cantú, Alex E Clark, Sandra L Leibel, Anahid Foroughishafiei, Anushka Saha, Abbas Hakim, Alhakam Nouri, Alma L Lastrella, Anelizze Castro-Martínez and 33 more

Abstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Rodolfo A Salido *Department of Bioengineering, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-0631-2817
Victor J Cantú *Department of Bioengineering, University of California San Diego, La Jolla, California, USA.
Alex E ClarkDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, USA.
Sandra L LeibelDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Anahid ForoughishafieiDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Anushka SahaDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Abbas HakimExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Alhakam NouriExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Alma L LastrellaExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Anelizze Castro-MartínezExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Ashley PlascenciaExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Bhavika K KapadiaExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Bing XiaExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Christopher A RuizExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Clarisse A MarotzDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-1520-8854
Daniel MaunderExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Elijah S LawrenceExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Elizabeth W SmootExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Emily EisnerExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Evelyn S CresciniExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Laura KohnHerbert Wertheim School of Public Health, University of California, La Jolla, California, USA.
Lizbeth Franco VargasExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Marisol ChacónExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Maryann BettyDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Michal MachnickiExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Min Yi WuExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Nathan A BaerExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Pedro Belda-FerreDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Peter De HoffSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Phoebe SeaverExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
R Tyler OstranderExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Rebecca TsaiDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.
Shashank SatheSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Stefan AignerSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Sydney C MorganSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Toan T NgoExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Tom BarberExpedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, California, USA.
Willi CheungSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Aaron F CarlinDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego School of Medicine, La Jolla, California, USA.
Gene W YeoSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Louise C LaurentSanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, California, USA.
Rebecca Fielding-MillerHerbert Wertheim School of Public Health, University of California, La Jolla, California, USA.
Rob KnightDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
SASEAU01HD108787 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELDING-MILLER, REBECCA KATHLEEN · 2022 to 2023
$2.4M
Training Program in Quantitative Integrative BiologyT32GM127235 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HWA, TERENCE · 2018 to 2022
$1.3M
Deconvolution of pro- and anti-viral responses to Dengue virus and Zika Virus infectionsK08AI130381 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CARLIN, AARON F. · 2019 to 2023
$1.0M
Social-structural and spatial determinants of HIV testing and linkage to care among high risk women in TanzaniaK01MH112436 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELDING-MILLER, REBECCA KATHLEEN · 2017 to 2021
$941k
Burroughs Wellcome Fund (BWF) Career Award for Medical ScientistsCounty of San Diego Health and Human Services Agency 563236HHS | National Institutes of Health (NIH) K01MH112436HHS | National Institutes of Health (NIH) K08AI130381NIAID NIH HHS K08 AI130381NIAID NIH HHS P30 AI036214NICHD NIH HHS U01 HD108787NIGMS NIH HHS T32 GM127235NIMH NIH HHS K01 MH112436
6 · The paper itself

Abstract

Environmental monitoring in public spaces can be used to identify surfaces contaminated by persons with coronavirus disease 2019 (COVID-19) and inform appropriate infection mitigation responses. Research groups have reported detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces days or weeks after the virus has been deposited, making it difficult to estimate when an infected individual may have shed virus onto a SARS-CoV-2-positive surface, which in turn complicates the process of establishing effective quarantine measures. In this study, we determined that reverse transcription-quantitative PCR (RT-qPCR) detection of viral RNA from heat-inactivated particles experiences minimal decay over 7 days of monitoring on eight out of nine surfaces tested. The properties of the studied surfaces result in RT-qPCR signatures that can be segregated into two material categories, rough and smooth, where smooth surfaces have a lower limit of detection. RT-qPCR signal intensity (average quantification cycle [

Indexed as

COVID-19environmental monitoringheat-inactivatedRT-qPCRSARS-CoV-2surface samplingswab

Identifiers

PMID34726486
PMCPMC8562474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.