Evidence map›Paper›PMID 34726122›Full record

ArticlePathogens and global health2022

The relevance of studying insect-nematode interactions for human disease.

Zorada Swart, Tuan A Duong, Brenda D Wingfield, Alisa Postma, Bernard Slippers

Open access · greenAbstract read
In one paragraph

Article in Pathogens and global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Effects of insecticidal proteins ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zorada SwartDepartment of Biochemistry Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, South Africa.ORCID 0000-0001-9158-3501
Tuan A DuongDepartment of Biochemistry Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, South Africa.ORCID 0000-0001-5110-1854
Brenda D WingfieldDepartment of Biochemistry Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, South Africa.ORCID 0000-0002-6189-1519
Alisa PostmaDepartment of Biochemistry Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, South Africa.ORCID 0000-0002-7842-8096
Bernard SlippersDepartment of Biochemistry Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute, University of Pretoria, South Africa.ORCID 0000-0003-1491-3858
University of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vertebrate-parasitic nematodes cause debilitating, chronic infections in millions of people worldwide. The burden of these so-called 'neglected tropical diseases' is often carried by poorer socioeconomic communities in part because research on parasitic nematodes and their vertebrate hosts is challenging and costly. However, complex biological and pathological processes can be modeled in simpler organisms. Here, we consider how insight into the interactions between entomopathogenic nematodes (EPN), their insect hosts and bacterial symbionts may reveal novel treatment targets for parasitic nematode infections. We argue that a combination of approaches that target nematodes, as well as the interaction of pathogens with insect vectors and bacterial symbionts, offer potentially effective, but underexplored opportunities.

Indexed as

NematodaAnimalsBacteriaHumansInsectaalternative treatment optionsentomopathogenic nematodesinter-species interactionsmodel organismsvector controlVertebrate-parasitic nematodes

Identifiers

PMID34726122
PMCPMC9090338
OpenAlexW3209144996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.