Evidence map›Paper›PMID 34725781›Full record

SynthesisHeart failure reviews2022

Effects of bromocriptine in peripartum cardiomyopathy: a systematic review and meta-analysis.

Angkawipa Trongtorsak, Veraprapas Kittipibul, Sunita Mahabir, Michel Ibrahim, Garly R Saint Croix, Gabriel A Hernandez, Sandra Chaparro

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Heart failure reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06250257 (Effect of Bromocriptine in Dilated Cardiomyopathy in Women of Reproductive Age), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06250257 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Bromocriptine in Dilated Cardiomyopathy in Women of Reproductive Age: A Hospital-Based Randomized Open Label Placebo-controlled Clinical Trial

TypeinterventionalSponsorJimma UniversityRan2024 to 2026Enrolled112ConditionsDilated CardiomyopathyArmsBromocriptine mesylate plus standard GDMT
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Lactation and cardiovascular health: A comprehensive review.American heart journal plus : cardiology research and practice · 2025
    Review
  9. Article
  10. Observational
  11. Observational
  12. Pharmacological interventions for peripartum cardiomyopathy.The Cochrane database of systematic reviews · 2024
    Article
  13. What Do We Know about Peripartum Cardiomyopathy? Yesterday, Today, Tomorrow.International journal of molecular sciences · 2024
    Review
  14. Review
  15. The inflammatory spectrum of cardiomyopathies.Frontiers in cardiovascular medicine · 2024
    Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Angkawipa TrongtorsakDepartment of Medicine, AMITA Health Saint Francis Hospital, IL, Evanston, USA. angkawipa.t@gmail.com.ORCID 0000-0003-1855-029X
Veraprapas KittipibulDivision of Cardiology, Duke University Medical Center, Durham, NC, USA.
Sunita MahabirCardiovascular Institute, Allegheny Health Network, Pittsburgh, PA, USA.
Michel IbrahimSection of Cardiology, Temple University, Philadelphia, PA, USA.
Garly R Saint CroixDivision of Cardiology, Columbia University at Mount Sinai Medical Center, Miami Beach, FL, USA.
Gabriel A HernandezDivision of Cardiovascular Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Sandra ChaparroAdvanced Heart Failure Program, Baptist Health South Florida, Miami, FL, USA.
Allegheny Health Network · USBaptist Health South Florida · USDuke Medical Center · USMount Sinai Medical Center · USSaint Francis Hospital · USTemple University · USUniversity of Mississippi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripartum cardiomyopathy (PPCM) is a rare but potentially life-threatening form of heart failure (HF). Bromocriptine, a dopamine D2 agonist, has been used as an adjunctive treatment for PPCM with controversial benefits. A comprehensive literature search was conducted through June 2021. We included studies comparing the outcomes of PPCM with or without bromocriptine use. Pooled risk ratio (RR) with 95% confidence intervals (CI) and I

Indexed as

CardiomyopathiesHeart FailurePregnancy Complications, CardiovascularBromocriptineFemaleHumansPeripartum PeriodPregnancyRandomized Controlled Trials as TopicStroke VolumeVentricular Function, LeftBromocriptineBromocriptineDopamine agonistHeart failurePeripartum cardiomyopathy

Identifiers

PMID34725781
OpenAlexW3210370617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.