Evidence map›Paper›PMID 34725724›Full record

ArticleActa diabetologica2022

Fasting plasma glucose level to guide the need for an OGTT to screen for gestational diabetes mellitus.

Kaat Beunen, Astrid Neys, Paul Van Crombrugge, Carolien Moyson, Johan Verhaeghe, Sofie Vandeginste, Hilde Verlaenen, Chris Vercammen, Toon Maes, Els Dufraimont and 11 more

Abstract read
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In one paragraph

Article in Acta diabetologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Postprandial Hyperglycaemia Screening and Pregnancy Outcomes-Lessons From COVID -19.The Australian & New Zealand journal of obstetrics & gynaecology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Kaat BeunenDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. kaat.beunen@kuleuven.be.ORCID http://orcid.org/0000-0003-3557-0022
Astrid NeysKU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Paul Van CrombruggeDepartment of Endocrinology, OLV Ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Carolien MoysonDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Johan VerhaegheDepartment of Obstetrics and Gynecology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Sofie VandeginsteDepartment of Obstetrics and Gynecology, OLV Ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Hilde VerlaenenDepartment of Obstetrics and Gynecology, OLV Ziekenhuis Aalst-Asse-Ninove, Moorselbaan 164, 9300, Aalst, Belgium.
Chris VercammenDepartment of Endocrinology, Imelda Ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Toon MaesDepartment of Endocrinology, Imelda Ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Els DufraimontDepartment of Obstetrics and Gynecology, Imelda Ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Nele RoggenDepartment of Obstetrics and Gynecology, Imelda Ziekenhuis, Imeldalaan 9, 2820, Bonheiden, Belgium.
Christophe De BlockDepartment of Endocrinology-Diabetology-Metabolism, Antwerp University Hospital, Drie Eikenstraat 655, 2650, Edegem, Belgium.
Yves JacquemynDepartment of Obstetrics and Gynecology, Antwerp University Hospital, Drie Eikenstraat 655, 2650, Edegem, Belgium.
Farah MekahliDepartment of Endocrinology, Kliniek St-Jan Brussel, Kruidtuinlaan 32, 1000, Brussel, Belgium.
Katrien De ClippelDepartment of Obstetrics and Gynecology, Kliniek St-Jan Brussel, Kruidtuinlaan 32, 1000, Brussel, Belgium.
Annick Van Den BruelDepartment of Endocrinology, AZ St Jan Brugge, Ruddershove 10, 8000, Brugge, Belgium.
Anne LoccufierDepartment of Obstetrics and Gynecology, AZ St Jan Brugge, Ruddershove 10, 8000, Brugge, Belgium.
Annouschka LaenenCenter of Biostatics and Statistical Bioinformatics, KU Leuven, Kapucijnenvoer 35 bloc d, box 7001, 3000, Leuven, Belgium.
Roland DevliegerDepartment of Obstetrics and Gynecology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Chantal MathieuDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Katrien BenhalimaDepartment of Endocrinology, University Hospital Gasthuisberg, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine the fasting plasma glucose (FPG) level at which an oral glucose tolerance test (OGTT) could be avoided to screen for gestational diabetes (GDM) and to evaluate the characteristics of women across this FPG threshold.

methodsA multi-centric prospective cohort study with 1843 women receiving universal screening for GDM with a 75 g OGTT.

resultsIn the total population, GDM prevalence was 12.5% (231). A FPG < 78 mg/dL was the cut-off with best trade-off to limit the number of missed GDM cases [44 (19.0%)] with a negative predictive value of 97.3% (95% CI 96.5-98.0) for GDM, while avoiding 52.2% OGTTs. Compared to GDM with FPG ≥ 78 mg/dL [187 (81.0%)], GDM women with FPG < 78 mg/dL had a significantly lower BMI (27.1 ± 4.5 vs. 29.6 ± 5.2 kg/m

conclusionsFPG < 78 mg/dL can be used to limit the number of OGTTs when screening for GDM. Women with FPG < 78 mg/dL had a better metabolic profile and in NGT women also less fetal overgrowth.

Indexed as

Diabetes, GestationalBlood GlucoseFastingFemaleFetal MacrosomiaGlucose Tolerance TestHumansPregnancyProspective StudiesBlood GlucoseFasting plasma glucoseGestational diabetes mellitusPregnancy outcomesScreening

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.