Evidence map›Paper›PMID 34725630›Full record

ReviewCurrent hepatology reports2021

Diagnostic Testing for SARS-CoV-2 Infection.

Emmanuel Thomas, Stephanie Delabat, David M Andrews

Abstract readReview
In one paragraph

Review in Current hepatology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emmanuel ThomasDepartment of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL USA.ORCID 0000-0003-1416-3903
Stephanie DelabatDepartment of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL USA.
David M AndrewsDepartment of Pathology, University of Miami Miller School of Medicine, Miami, FL USA.

Funding

A MULTIFACETED APPROACH TO STUDY TISSUE AND CELL TYPE SPECIFIC MOLECULAR MECHANISMS OF THE HOST RESPONSE TO ACUTE/CHRONIC VIRAL INFECTIONR35GM124915 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Emmanuel Thomas · 2017 to 2026
$3.9M
NIGMS NIH HHS R35 GM124915
6 · The paper itself

Abstract

purpose of reviewGiven the rapid development of diagnostic approaches to test for and diagnose infection with SARS-CoV-2, many options are available to assess infection. Multiple established diagnostic companies are now providing testing platforms whereas initially, testing was being performed with simple PCR-based tests using standard laboratory reagents. RECENT

findingsAdditional testing platforms continue to be developed but challenges with testing, including obtaining testing reagents and other related supplies, are frequently encountered. With time, the testing supply chain will improve and more companies will be providing materials to support these testing efforts. In the USA, the need for rapid assay development and subsequent approval through attainment of emergency use authorization (EUA) has superseded the traditional arduous diagnostic testing approval workflow mandated by the FDA. It is anticipated that the USA will be able to continue to significantly increase its testing capabilities to address this pandemic; however, challenges remain due to the diversity of the performance characteristics of tests being utilized. SUMMARY: This review provides an overview of the current diagnostic testing landscape, with pertinent information related to SARS-CoV-2 virology and antibody responses, that is available to diagnose infection.

Indexed as

AntibodyAntigenCOVID-19Nucleic acidsPCRSARS-CoV-2

Identifiers

PMID34725630
PMCPMC8550867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.