Evidence map›Paper›PMID 34725572›Full record

ArticleRehabilitation research and practice2021

Dynamic Balance in Spinal and Bulbar Muscular Atrophy: Relationship between Strength and Performance of Forward Lunge, Step Up and Over, and Step Quick Turn.

Joseph A Shrader, Ashwini Sansare, Vincent Shieh, Joshua G Woolstenhulme, Julie Rekant, Rafael Jiménez-Silva, Galen O Joe, Angela Kokkinis, Kenneth H Fischbeck, Christopher Grunseich and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rehabilitation research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Frequency and Circumstances of Falls Events in People Living With Spinal and Bulbar Muscular Atrophy: A Cross-Sectional Survey.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Joseph A ShraderRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0001-8174-0745
Ashwini SansareRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0002-3218-1649
Vincent ShiehRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0003-2290-3676
Joshua G WoolstenhulmeRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0002-6754-9036
Julie RekantRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Rafael Jiménez-SilvaRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Galen O JoeRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Angela KokkinisNeurogenetics Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
Kenneth H FischbeckNeurogenetics Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
Christopher GrunseichNeurogenetics Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
Cristiane ZampieriRehabilitation Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health Clinical Center · USNational Institute of Neurological Disorders and Stroke · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpinal and bulbar muscular atrophy (SBMA) is a neuromuscular disorder that leads to progressive weakness of bulbar and extremity muscles. Dynamic balance during functional tasks has not been reported in people with SBMA.

objectives(1) To evaluate the ability to safely complete a forward lunge (FL), step quick turn (SQT), and step up and over (SUO), (2) to determine the presence and severity of dynamic balance impairments by comparing performance to normative data, and (3) to investigate the relationship between lower extremity strength and ability to complete each task.

designCross-sectional analysis.

resultsThe most difficult test, per completion rate, was SUO (52%), followed by FL (57%) and SQT (65%).

conclusionsConsiderable dynamic balance abnormalities were observed. Lower extremity strength helps explain low test completion rates. Patients modified task movement patterns, enabling safe task performance. Study results can help direct patient care and future protocol design for people with SBMA.

Identifiers

PMID34725572
PMCPMC8557083
OpenAlexW3208927959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.