Evidence map›Paper›PMID 34725570›Full record

ReviewJournal of ophthalmology2021

The Contemporary Role of Photodynamic Therapy in the Treatment of Pachychoroid Diseases.

Lawrence P L Iu, Ho Yan Chan, Mary Ho, Frank H P Lai, Andrew C Y Mak, Raymond L M Wong, Alvin L Young

Open access · goldAbstract readReview
In one paragraph

Review in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Intraocular Metastasis: Differential Diagnosis and Management.Clinical & experimental ophthalmology · 2026
    Review
  2. Pachychoroid diseases of the macula: an update.Medical hypothesis, discovery & innovation ophthalmology journal · 2026
    Review
  3. Article
  4. Pachychoroid Spectrum Disorders: An Updated Review.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lawrence P L IuDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.ORCID https://orcid.org/0000-0001-6898-5043
Ho Yan ChanDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.
Mary HoDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.ORCID https://orcid.org/0000-0001-8864-2988
Frank H P LaiDepartment of Ophthalmology, Caritas Medical Centre, Sham Shui Po, Hong Kong.ORCID https://orcid.org/0000-0002-4446-3790
Andrew C Y MakDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.
Raymond L M WongDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID https://orcid.org/0000-0002-0149-6162
Alvin L YoungDepartment of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Shatin, Hong Kong.
Chinese University of Hong Kong · HKCaritas Medical Centre · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in retinal imaging technology have improved our understanding in the pathogenesis and evolvement of various chorioretinal diseases. Central serous chorioretinopathy and polypoidal choroidal vasculopathy are now recognized to belong to the same spectrum of disorders known as pachychoroid diseases. Pachychoroid diseases have similar pathogenesis pathway and common characteristics of thickened choroid, dilated outer choroidal vessels, and thinning of choriocapillaris. More disease entities have been identified to belong to this disease spectrum. Photodynamic therapy can induce choroidal hypoperfusion, remodeling of abnormal choroidal vessels, and reduction of choroidal congestion. It is known to be an effective treatment for chronic central serous chorioretinopathy and polypoidal choroidal vasculopathy. Many new studies are being performed to investigate its efficacy in other pachychoroid diseases. In this review, we provided an overview of the rationale, efficacy, and treatment strategies of photodynamic therapy in different pachychoroid diseases and discussed its role in the management along with other treatment modalities with most updated clinical evidence.

Identifiers

PMID34725570
PMCPMC8556979
OpenAlexW3209222885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.