Evidence map›Paper›PMID 34725491›Full record

ArticleNature chemistry2022

Weakly hydrated anions bind to polymers but not monomers in aqueous solutions.

Bradley A Rogers, Halil I Okur, Chuanyu Yan, Tinglu Yang, Jan Heyda, Paul S Cremer

Abstract read
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In one paragraph

Article in Nature chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 112 citations in OpenAlex.

  1. Water Structure within Ternary Solvents Suggests Nanophase Formation.Journal of the American Chemical Society · 2026
    Article
  2. ATP Can Act as a Stabilizer on Neutral Macromolecules.The journal of physical chemistry letters · 2025
    Article
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  11. Specific Ion Effects in Hydrogels.Molecules (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Greasy Cations Bind to Neutral Macromolecules in Aqueous Solution.The journal of physical chemistry letters · 2024
    Article
  17. Influence of HChemical science · 2024
    Article
  18. Assessing Weak Anion Binding to Small Peptides.The journal of physical chemistry. B · 2024
    Article
  19. Solvent effects in anion recognition.Nature reviews. Chemistry · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Bradley A RogersDepartment of Chemistry, The Pennsylvania State University, University Park, PA, USA.
Halil I OkurDepartment of Chemistry, The Pennsylvania State University, University Park, PA, USA.
Chuanyu YanDepartment of Chemistry, The Pennsylvania State University, University Park, PA, USA.
Tinglu YangDepartment of Chemistry, The Pennsylvania State University, University Park, PA, USA.
Jan HeydaDepartment of Physical Chemistry, University of Chemistry and Technology, Prague, Dejvice, Czech Republic.ORCID http://orcid.org/0000-0002-9428-9508
Paul S CremerDepartment of Chemistry, The Pennsylvania State University, University Park, PA, USA. psc11@psu.edu.ORCID http://orcid.org/0000-0002-8524-0438
Pennsylvania State University · USUniversity of Chemistry and Technology, Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Weakly hydrated anions help to solubilize hydrophobic macromolecules in aqueous solutions, but small molecules comprising the same chemical constituents precipitate out when exposed to these ions. Here, this apparent contradiction is resolved by systematically investigating the interactions of NaSCN with polyethylene oxide oligomers and polymers of varying molecular weight. A combination of spectroscopic and computational results reveals that SCN

Identifiers

PMID34725491
OpenAlexW3210060032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.