ArticleScientific reports2021
Local adaptations of Mediterranean sheep and goats through an integrative approach.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Follicular dynamics, cumulus-oocyte complex recovery, and reproductive resilience in local Algerian ewes during seasonal anestrus.Tropical animal health and production · 2026Article
- Winter-summer contrasts in metabolic, hormonal, and reproductive function of local buck goats in Mediterranean semi-extensive systems.Tropical animal health and production · 2026Article
- An Analysis of Small-Ruminant Farming in Marginal Area of the Mediterranean Region: A Focus on the Gentile di Puglia Breed.Animals : an open access journal from MDPI · 2026Review
- Genomic analysis reveals convergent signatures of selection for milk traits in sheep and goats.Journal of animal science and biotechnology · 2026Article
- Detection of homozygosity and heterozygosity regions in mediterranean sheep breeds revealed by high-density SNP array.Journal of animal science · 2026Article
- Genetic diversity, population structure, and combined detection of selection signatures in Iranian versus Afghan Baluchi sheep.PloS one · 2026Article
- Whole-genome resequencing of the Kazakh coarse-wool fat-tailed sheep identifies functional variants in disease-associated genes.Frontiers in veterinary science · 2026Article
- Effects of seasonality and different rearing systems on the behavior and thermal comfort of sheep in the northern region of Brazil, eastern Amazon.Frontiers in veterinary science · 2026Article
- Integrating whole-genome resequencing data reveals adaptive selection signatures in sheep populations under extreme environments.BMC genomics · 2025Article
- Genome scan for runs of homozygosity in Saanen goats selected under tropical environments reveals candidate genes for adaptive and production traits.Tropical animal health and production · 2025Article
- A comprehensive genome-wide analysis for signatures of selection in goat (genus Capra) revealed new candidate genes for environmental adaptation and productive traits.BMC genomics · 2025Article
- Genomic analyses of Asiatic Mouflon in Iran provide insights into the domestication and evolution of sheep.Genetics, selection, evolution : GSE · 2025Article
- Article
- Genomic Characterization of Crossbred-Driven Adaptation in the Endangered Yangba Cattle of China.Animals : an open access journal from MDPI · 2025Article
- Genetic advancements and future directions in ruminant livestock breeding: from reference genomes to multiomics innovations.Science China. Life sciences · 2025Review
- Genome-wide landscape of genetic diversity, runs of homozygosity, and runs of heterozygosity in five Alpine and Mediterranean goat breeds.Journal of animal science and biotechnology · 2025Article
- Climate resilience in goats: a comprehensive review of the genetic basis for adaptation to varied climatic conditions.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Review
- Article
- Assessment of breeding nuclei contributions to the genetic diversity and population structure of the Cyprus Chios sheep.Scientific reports · 2024Article
- Molecular Characteristics and Processing Technologies of Dairy Products from Non-Traditional Species.Molecules (Basel, Switzerland) · 2024Review
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15 authors.
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Abstract
Small ruminants are suited to a wide variety of habitats and thus represent promising study models for identifying genes underlying adaptations. Here, we considered local Mediterranean breeds of goats (n = 17) and sheep (n = 25) from Italy, France and Spain. Based on historical archives, we selected the breeds potentially most linked to a territory and defined their original cradle (i.e., the geographical area in which the breed has emerged), including transhumant pastoral areas. We then used the programs PCAdapt and LFMM to identify signatures of artificial and environmental selection. Considering cradles instead of current GPS coordinates resulted in a greater number of signatures identified by the LFMM analysis. The results, combined with a systematic literature review, revealed a set of genes with potentially key adaptive roles in relation to the gradient of aridity and altitude. Some of these genes have been previously implicated in lipid metabolism (SUCLG2, BMP2), hypoxia stress/lung function (BMPR2), seasonal patterns (SOX2, DPH6) or neuronal function (TRPC4, TRPC6). Selection signatures involving the PCDH9 and KLH1 genes, as well as NBEA/NBEAL1, were identified in both species and thus could play an important adaptive role.
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