ArticleScientific reports2021
A novel wastewater-based epidemiology indexing method predicts SARS-CoV-2 disease prevalence across treatment facilities in metropolitan and regional populations.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- A smartphone-powered decentralized microfluidic platform for sensitive CRISPR-based nucleic acid detection.Microsystems & nanoengineering · 2026Article
- Wastewater Measures of SARS-CoV-2 Accurately Predict Frequency of Symptomatic Infections in the Community.The Journal of infectious diseases · 2025Observational
- Article
- Multi-scale wastewater surveillance at a Bangkok tertiary care hospital: A potential sentinel site for real-time COVID-19 surveillance at hospital and national levels.PLOS global public health · 2025Article
- Public health use and lessons learned from a statewide SARS-CoV-2 wastewater monitoring program (MiNET).Heliyon · 2024Article
- Advancing Public Health Surveillance: Integrating Modeling and GIS in the Wastewater-Based Epidemiology of Viruses, a Narrative Review.Pathogens (Basel, Switzerland) · 2024Review
- Data-driven systematic analysis of waterborne viruses and health risks during the wastewater reclamation process.Environmental science and ecotechnology · 2024Article
- Structured Ethical Review for Wastewater-Based Testing in Support of Public Health.Environmental science & technology · 2023Article
- Using Wastewater Surveillance to Monitor Gastrointestinal Pathogen Infections in the State of Oklahoma.Microorganisms · 2023Article
- Understanding common population markers for SARS-CoV-2 RNA normalization in wastewater - A review.Chemosphere · 2023Review
- Structured Ethical Review for Wastewater-Based Testing.medRxiv : the preprint server for health sciences · 2023Article
- SARS-CoV-2 concentration in wastewater consistently predicts trends in COVID-19 case counts by at least two days across multiple WWTP scales.Environmental advances · 2023Article
- Statistical Analysis of SARS-CoV-2 Using Wastewater-Based Data of Stockholm, Sweden.International journal of environmental research and public health · 2023Article
- Regional and temporal differences in the relation between SARS-CoV-2 biomarkers in wastewater and estimated infection prevalence - Insights from long-term surveillance.The Science of the total environment · 2023Article
- A multistate assessment of population normalization factors for wastewater-based epidemiology of COVID-19.PloS one · 2023Article
- Using geographic information systems to link population estimates to wastewater surveillance data in New York State, USA.PLOS global public health · 2023Article
- Expansion of wastewater-based disease surveillance to improve health equity in California's Central Valley: sequential shifts in case-to-wastewater and hospitalization-to-wastewater ratios.Frontiers in public health · 2023Article
- Assessment of a mass balance equation for estimating community-level prevalence of COVID-19 using wastewater-based epidemiology in a mid-sized city.Scientific reports · 2022Article
- Assessing wastewater-based epidemiology for the prediction of SARS-CoV-2 incidence in Catalonia.Scientific reports · 2022Article
- Wastewater based epidemiology as a silent sentinel of the trend of SARS-CoV-2 circulation in the community in central Argentina.Water research · 2022Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
There is a need for wastewater based epidemiological (WBE) methods that integrate multiple, variously sized surveillance sites across geographic areas. We developed a novel indexing method, Melvin's Index, that provides a normalized and standardized metric of wastewater pathogen load for qPCR assays that is resilient to surveillance site variation. To demonstrate the utility of Melvin's Index, we used qRT-PCR to measure SARS-CoV-2 genomic RNA levels in influent wastewater from 19 municipal wastewater treatment facilities (WWTF's) of varying sizes and served populations across the state of Minnesota during the Summer of 2020. SARS-CoV-2 RNA was detected at each WWTF during the 20-week sampling period at a mean concentration of 8.5 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.