Evidence map›Paper›PMID 34725379›Full record

Trial reportScientific reports2021

No aftereffects of high current density 10 Hz and 20 Hz tACS on sensorimotor alpha and beta oscillations.

Louis-Philippe Lafleur, Audrey Murray, Manon Desforges, Kevin Pacheco-Barrios, Felipe Fregni, Sara Tremblay, Dave Saint-Amour, Jean-François Lepage, Hugo Théoret

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  5. Transcranial alternating current stimulation can modulate the blink reflex excitability. Effects of a 10- and 20-Hz tACS session on the blink reflex recovery cycle in healthy subjects.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Louis-Philippe LafleurDépartement de Psychologie, Université de Montréal, CP 6128. Succ. Centre-Ville, Montréal, QC, H3C 3J7, Canada.
Audrey MurrayDépartement de Psychologie, Université du Québec à Montréal, Montréal, Canada.
Manon DesforgesDépartement de Psychoéducation et de Psychologie, Université du Québec en Outaouais, Gatineau, Canada.
Kevin Pacheco-BarriosNeuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Felipe FregniNeuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Sara TremblayDépartement de Psychoéducation et de Psychologie, Université du Québec en Outaouais, Gatineau, Canada.
Dave Saint-AmourDépartement de Psychologie, Université du Québec à Montréal, Montréal, Canada.
Jean-François LepageDépartement de Pédiatrie, Faculté de Médecine et des Sciences de la Santé de l'Université de Sherbrooke, Centre de Recherche du CHU Sherbrooke, Sherbrooke, Canada.
Hugo ThéoretDépartement de Psychologie, Université de Montréal, CP 6128. Succ. Centre-Ville, Montréal, QC, H3C 3J7, Canada. hugo.theoret@umontreal.ca.
Centre Hospitalier Universitaire Sainte-Justine · CAMassachusetts General Hospital · USUniversité du Québec en Outaouais · CAUniversité de Montréal · CAUniversité de Sherbrooke · CAUniversité du Québec à Montréal · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2016-05079
6 · The paper itself

Abstract

Application of transcranial alternating current stimulation (tACS) is thought to modulate ongoing brain oscillations in a frequency-dependent manner. However, recent studies report various and sometimes inconsistent results regarding its capacity to induce changes in cortical activity beyond the stimulation period. Here, thirty healthy volunteers participated in a randomized, cross-over, sham-controlled, double-blind study using EEG to measure the offline effects of tACS on alpha and beta power. Sham and high current density tACS (1 mA; 10 Hz and 20 Hz; 0.32 mA/cm

Indexed as

Alpha RhythmBeta RhythmAdolescentAdultBayes TheoremBrainBrain MappingDouble-Blind MethodElectroencephalographyFemaleFinite Element AnalysisHealthy VolunteersHumansMaleModels, NeurologicalNeuronal Plasticity

Identifiers

PMID34725379
PMCPMC8560917
OpenAlexW3209363227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.