Evidence map›Paper›PMID 34725342›Full record

ReviewCell death & disease2021

"Ryanopathies" and RyR2 dysfunctions: can we further decipher them using in vitro human disease models?

Yvonne Sleiman, Alain Lacampagne, Albano C Meli

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Cell death & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. VMP1 forms a CaScience advances · 2026
    Article
  3. Article
  4. Article
  5. Calcium release channel deficiency syndrome in patients diagnosed with idiopathic ventricular fibrillation and decedents classified as sudden unexplained death in the young.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Palmitoylation in cardiovascular diseases: Molecular mechanism and therapeutic potential.International journal of cardiology. Heart & vasculature · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Ion channel trafficking implications in heart failure.Frontiers in cardiovascular medicine · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. How Functional Genomics Can Keep Pace With VUS Identification.Frontiers in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yvonne SleimanPhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France.
Alain LacampagnePhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France.ORCID http://orcid.org/0000-0003-0264-1787
Albano C MeliPhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France. albano.meli@inserm.fr.ORCID http://orcid.org/0000-0002-1727-3027
Centre National de la Recherche Scientifique · FR

Funding

AFM-Téléthon (French Muscular Dystrophy Association) 20225
6 · The paper itself

Abstract

The regulation of intracellular calcium (Ca

Indexed as

DiseaseModels, BiologicalAnimalsHumansInduced Pluripotent Stem CellsMultiple Organ FailureMutationRyanodine Receptor Calcium Release ChannelRyanodine Receptor Calcium Release Channel

Identifiers

PMID34725342
PMCPMC8560800
OpenAlexW3209458511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.