Evidence map›Paper›PMID 34725210›Full record

ArticleOccupational and environmental medicine2022

Lifetime high occupational physical activity and total and cause-specific mortality among 320 000 adults in the NIH-AARP study: a cohort study.

David Martinez Gomez, Pieter Coenen, Carlos Celis-Morales, Jorge Mota, Fernando Rodriguez-Artalejo, Charles Matthews, Pedro F Saint-Maurice

Open access · greenAbstract read
In one paragraph

Article in Occupational and environmental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

David Martinez GomezPreventive Medicina and Public Health, Universidad Autonoma de Madrid, Madrid, Spain d.martinez@uam.es.ORCID 0000-0002-9598-019X
Pieter CoenenDepartment of Public and Occupational Health, Amsterdam UMC - Locatie VUMC, Amsterdam, Netherlands.ORCID 0000-0002-4034-7063
Carlos Celis-MoralesInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Jorge MotaResearch Center on Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal.
Fernando Rodriguez-ArtalejoPreventive Medicina and Public Health, Universidad Autonoma de Madrid, Madrid, Spain.
Charles MatthewsNational Cancer Institute, Bethesda, Maryland, USA.
Pedro F Saint-MauriceNational Cancer Institute, Bethesda, Maryland, USA.
National Cancer Institute · USAmsterdam University Medical Centers · NLMadrid Institute for Advanced Studies · ESUniversidad Autónoma de Madrid · ESUniversidade do Porto · PTUniversity of Glasgow · GB

Funding

Prospective Studies of Diet and Cancer in the AARP CohortZIACP010196 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SINHA, RASHMI · 2009 to 2025
$21.0M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

objectivesWe examined the associations of history and duration in high occupational physical activity (OPA) with long-term total and cause-specific mortality.

methodsThe sample included 322 126 participants (135 254 women) from the National Institutes of Health-AARP Diet and Health Study, established in 1995-1996. History and duration in high OPA were reported by participants. All-cause, cardiovascular, cancer and other cause mortality records available through 31 December 2011.

resultsThe prevalence of high OPA was 52.1% in men and 16.1% in women. During 13.6 years (SD, 3.3) of follow-up, 73 563 participants (25 219 women) died. In age-adjusted models, the risk of death was higher among men (HR 1.14, 95% CI 1.12 to 1.16) and women (HR 1.22, 95% CI 1.18 to 1.26) with a history of high OPA. However, these associations were substantially attenuated in women (HR 1.04, 95% CI 1.00 to 1.07, an 81.8% attenuation) and eliminated in men (HR 1.02, 95% CI 0.99 to 1.04, 85.7% attenuation) after multivariable adjustments. Similar important attenuation results were found when examining duration in high OPA, as well as using cause-specific deaths as the outcomes. Educational attainment and smoking patterns were the main contributors in the excess mortality among people working in highly physically active jobs in both men and women.

conclusionParticipating in high OPA was not consistently associated with a higher mortality risk, after adjustments for education and smoking factors. Workers in high OPA should be aware that they might not be getting all well-known health benefits of being physically active if they are only very active at work.

Indexed as

Cardiovascular DiseasesExerciseAdultCause of DeathCohort StudiesFemaleHumansMaleMortalityNational Institutes of Health (U.S.)OccupationsRisk FactorsUnited Statesexercisemortalityoccupational healthphysical exertionpreventive medicine

Identifiers

PMID34725210
PMCPMC12309917
OpenAlexW3211308937

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.