Evidence map›Paper›PMID 34725102›Full record

ArticleeNeuro

RapID Cell Counter: Semi-Automated and Mid-Throughput Estimation of Cell Density within Diverse Cortical Layers.

Aarthi Sekar, Thiago M Sanches, Keiko Hino, Matangi Kumar, Juliann Wang, Elisa Ha, Blythe Durbin-Johnson, Sergi Simó, Megan Y Dennis

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axis.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Aarthi SekarIntegrated Genetics and Genomics Graduate Group, University of California, Davis, CA, 95616.
Thiago M SanchesIntegrated Genetics and Genomics Graduate Group, University of California, Davis, CA, 95616.
Keiko HinoDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA, 95616.
Matangi KumarGenome Center, University of California, Davis, CA, 95616.
Juliann WangGenome Center, University of California, Davis, CA, 95616.
Elisa HaGenome Center, University of California, Davis, CA, 95616.
Blythe Durbin-JohnsonDepartment of Public Health Sciences, University of California, Davis, CA, 95616.
Sergi SimóDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA, 95616 mydennis@ucdavis.edu ssimo@ucdavis.edu.
Megan Y DennisIntegrated Genetics and Genomics Graduate Group, University of California, Davis, CA, 95616 mydennis@ucdavis.edu ssimo@ucdavis.edu.ORCID 0000-0002-8502-5420
University of California System · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
UC Davis MCB T32 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility (DEIA) MentorshipT32GM007377 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEDIN, FREDERIC LOUIS · 1985 to 2023
$9.9M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JUDY A. VAN DE WATER · 2020 to 2026
$9.7M
The function of duplicated genes in human brain evolution and diseaseDP2MH119424 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DENNIS, MEGAN Y · 2018 to 2018
$2.4M
Regulation of hippocampal morphogenesis and homeostasis by the E3 ubiquitin ligase CRL5R01NS109176 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SIMO, SERGI · 2019 to 2023
$1.7M
Characterization of Human-Specific Duplicated Genes Implicated in NeurocognitiveR00NS083627 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DENNIS, MEGAN Y · 2016 to 2018
$727k
NCATS NIH HHS UL1 TR001860NICHD NIH HHS P50 HD103526NIGMS NIH HHS T32 GM007377NIMH NIH HHS DP2 MH119424NINDS NIH HHS R00 NS083627NINDS NIH HHS R01 NS109176
6 · The paper itself

Abstract

Tracking and quantifying the abundance and location of cells in the developing brain is essential in neuroscience research, enabling a greater understanding of mechanisms underlying nervous system morphogenesis. Widely used experimental methods to quantify cells labeled with fluorescent markers, such as immunohistochemistry (IHC),

Indexed as

NeocortexNeuronsAnimalsAstrocytesCell CountComputer GraphicsGTPase-Activating ProteinsMiceMorphogenesisUser-Computer InterfaceGTPase-Activating ProteinsSrgap2 protein, mouseautomatedbrain imagingcell quantificationfluorescencemicroscopy

Identifiers

PMID34725102
PMCPMC8638678
OpenAlexW3209538691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.