Evidence map›Paper›PMID 34725066›Full record

ArticleBMJ case reports2021

Hemi-central retinal vein occlusion as a rare manifestation of the hypercoagulable state in COVID-19.

Jose R Russe-Russe, Alejandro Alvarez-Betancourt, Amanda Milburn, Prachi Anand

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The spectrum of COVID-19-associated chorioretinal vasculopathy.American journal of ophthalmology case reports · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jose R Russe-RusseInternal Medicine, Nassau University Medical Center, East Meadow, New York, USA joseramonrusserusse@gmail.com.ORCID http://orcid.org/0000-0001-7801-2165
Alejandro Alvarez-BetancourtInternal Medicine, Nassau University Medical Center, East Meadow, New York, USA.
Amanda MilburnCollege of Osteopathic Medicine, NYIT, Old Westbury, New York, USA.
Prachi AnandInternal Medicine/Rheumatology, Nassau University Medical Center, East Meadow, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, COVID-19 has no definite effective targeted therapy, and management is primarily supportive. Central retinal vein occlusion (CRVO) is frequently caused by systemic risk factors posing hypercoagulable states. In April 2020, a female patient with a history of hypertension, diabetes mellitus and chronic kidney disease presented with 2 days of loose, watery stools, nasal congestion and severe lethargy. The patient denied dyspnoea or fever. A week after the initial symptoms, the patient reported decreased vision from the left eye. Dilated funduscopy and fluorescein angiography suggested hemi-CRVO. The patient refused intravitreal antivascular endothelial growth factor agents because of non-severe visual loss. Testing was positive for COVID-19 IgG antibodies; reverse transcription PCR was not available. Vision improved within 3 weeks of presentation. We recommend that clinicians keep a high suspicion for acute onset of thrombotic events in patients with COVID-19 and thrombotic predisposing risk factors.

Indexed as

COVID-19Retinal Vein OcclusionFemaleFluorescein AngiographyHumansOphthalmoscopySARS-CoV-2COVID-19retinavenous thromboembolism

Identifiers

PMID34725066
PMCPMC8562529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.