Evidence map›Paper›PMID 34724923›Full record

ArticleBMC infectious diseases2021

The serotype distribution of Streptococcus agalactiae (GBS) carriage isolates among pregnant women having risk factors for early-onset GBS disease: a comparative study with GBS causing invasive infections during the same period in Denmark.

Hans-Christian Slotved, Jens Kjølseth Møller, Mohammad Rohi Khalil, Stine Yde Nielsen

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  7. First Report ofMicroorganisms · 2025
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  8. Genomic features and pathogenic potential ofJournal of advanced veterinary and animal research · 2025
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  10. Antibiotic Resistance and Serotypes Distribution inPolish journal of microbiology · 2024
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  12. Review
  13. Article
  14. Article
  15. Prevalence, risk factors, and serotypes of group BTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Hans-Christian SlotvedDepartment of Bacteria, Parasites and, Fungi, Statens Serum Institut, Artillerivej 5, DK-2300, Copenhagen, Denmark. hcs@ssi.dk.
Jens Kjølseth MøllerDepartment of Clinical Microbiology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.
Mohammad Rohi KhalilDepartment of Gynecology and Obstetrics, Kolding Hospital, University Hospital of Southern Denmark, Kolding, Denmark.
Stine Yde NielsenDepartment of Clinical Microbiology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.
Aarhus University · DKKolding Hospital · DKStatens Serum Institut · DKVejle Sygehus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe the serotype distribution of Streptococcus agalactiae (GBS) carriage isolates from women in labor and among GBS isolates causing invasive infections during the same period to see if the distribution of carriage serotypes reflects the GBS serotypes causing invasive diseases including early-onset disease (EOGBS).

methodsData on invasive isolates from 2019 including serotype, erythromycin and clindamycin susceptibility was retrieved from the Danish national reference laboratory, Statens Serum Institut. Carriage isolates were collected from women with risk factors for EOGBS enrolled at delivery at the maternity ward at a Danish University Hospital, first half of 2019.

resultsAmong carriage isolates, the dominant serotype was IX (21 %) followed by serotype III (19 %). The resistance to erythromycin and clindamycin was 21 and 26 %, respectively. Among invasive GBS isolates, no case of EOGBS with serotype IX was detected but the distribution of serotypes were otherwise similar to the GBS carrier strains. The corresponding resistance to erythromycin and clindamycin was 23  and 15 %, respectively. Penicillin resistance was not detected among carriage nor invasive isolates.

conclusionsThe distribution of serotypes among carriage and invasive GBS reflects the assumption that EOGBS occur following transmission of GBS from mother to newborn, with the exception of serotype IX.

Indexed as

Streptococcal InfectionsStreptococcus agalactiaeAnti-Bacterial AgentsDenmarkDrug Resistance, BacterialFemaleHumansInfant, NewbornMicrobial Sensitivity TestsPregnancyPregnant PeopleRisk FactorsSerogroupAnti-Bacterial AgentsAntimicrobial susceptibilityCarriageEOGBSGroup B streptococciPregnancyStreptococcus agalactiae

Identifiers

PMID34724923
PMCPMC8561911
OpenAlexW3209401222

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.