Evidence map›Paper›PMID 34724846›Full record

ArticleJournal of biological rhythms2022

Nitecap: An Exploratory Circadian Analysis Web Application.

Thomas G Brooks, Antonijo Mrčela, Nicholas F Lahens, Georgios K Paschos, Tilo Grosser, Carsten Skarke, Garret A FitzGerald, Gregory R Grant

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biological rhythms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pregnancy damps thermoregulatory rhythms across timescales through neural estrogen signaling in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Rhythmic Mechanisms Governing CAM Photosynthesis inInternational journal of molecular sciences · 2026
    Article
  8. Article
  9. Article
  10. Circadian clock communication during homeostasis and ageing.Nature reviews. Molecular cell biology · 2025
    Review
  11. Liver as a nexus of daily metabolic cross talk.International review of cell and molecular biology · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Integrative Analysis of Rhythmicity: From Biology to Urban Environments and Sustainability.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Thomas G BrooksInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-6980-0079
Antonijo MrčelaInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Nicholas F LahensInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Georgios K PaschosInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Tilo GrosserInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Carsten SkarkeInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-5145-3681
Garret A FitzGeraldInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Gregory R GrantInstitute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.
Translational Therapeutics (United States) · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Integrative Training in the Neurocircuitry of Affective DisordersT32MH106442 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI SHELINE, YVETTE I · 2016 to 2020
$1.1M
NCATS NIH HHS UL1 TR000003NIMH NIH HHS T32 MH106442
6 · The paper itself

Abstract

Circadian omics analyses present investigators with large amounts of data to consider and many choices for methods of analysis. Visualization is crucial as rhythmicity can take many forms and

Indexed as

ARNTL Transcription FactorsCircadian ClocksCircadian RhythmCLOCK ProteinsLiverSoftwareARNTL Transcription FactorsCLOCK Proteinscircadian analysisprincipal component analysisrhythmicity analysisvisualizationweb application

Identifiers

PMID34724846
PMCPMC9003665
OpenAlexW3209952744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.