Evidence map›Paper›PMID 34724811›Full record

ArticlemBio2021

SepA Enhances

Mario Meza-Segura, James R Birtley, Ana Maldonado-Contreras, Christian Mueller, Karl J Simin, Lawrence J Stern, Beth A McCormick

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. EnteroaggregativeEcoSal Plus · 2025
    Review
  2. SPATEs promote the survival ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Review
  4. Plasmid-encoded toxin ofFrontiers in cellular and infection microbiology · 2024
    Article
  5. Alpha-1-antitrypsin as novel substrate forFrontiers in immunology · 2024
    Article
  6. A Tale aboutMicroorganisms · 2023
    Review
  7. Review
  8. Article
  9. A Novel Adult Murine Model of Typical EnteroaggregativeFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mario Meza-Segura *Department of Microbiology and Physiological Systems, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
James R Birtley *Department of Pathology, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
Ana Maldonado-ContrerasDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
Christian MuellerHorae Gene Therapy Center, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
Karl J SiminDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
Lawrence J SternDepartment of Pathology, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
Beth A McCormickDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical Schoolgrid.168645.8, Worcester, Massachusetts, USA.
University of Massachusetts Chan Medical School · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Control of Neutrophilic Inflammation in Intestinal Health and DiseaseR01DK109677 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Beth A McCormick · 2016 to 2026
$5.2M
Structure and Function of MHC ProteinsR37AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J. · 2008 to 2017
$4.1M
Intestinal Homeostasis Induced by CommensalsR01DK125407 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCCORMICK, BETH A · 2020 to 2023
$2.2M
Structure and Function of Class II MHC ProteinsR01AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J · 1996 to 2006
$1.6M
Structure and Function of Class II MHC ProteinsR56AI038996 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STERN, LAWRENCE J · 2007 to 2007
$324k
NCATS NIH HHS UL1 TR001453NIAID NIH HHS R01 AI038996NIAID NIH HHS R37 AI038996NIAID NIH HHS R56 AI038996NIDDK NIH HHS R01 DK109677NIDDK NIH HHS R01 DK125407
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha 1-AntitrypsinBacterial ProteinsCell MovementChemotactic FactorsDysentery, BacillaryEpithelial CellsHumansIntestinesNeutrophilsShigellaalpha 1-AntitrypsinBacterial ProteinsChemotactic FactorsSepA protein, ShigellaSERPINA1 protein, humanalpha-1 antitrypsinchemotaxisgut inflammationneutrophilsShigella

Identifiers

PMID34724811
PMCPMC8561385
OpenAlexW3209148569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.