Evidence map›Paper›PMID 34724528›Full record

ArticleJAMA neurology2021

Citius, Fortius, Altius-Understanding Which Components Drive Exercise Benefits in Parkinson Disease.

Nienke M de Vries, Sirwan K L Darweesh, Bastiaan R Bloem

Registry-linked trialAbstract readComment
PubMed Publisher
In one paragraph

Article in JAMA neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07324330 (Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07324330 narecruitingnot on this mapstarted 2025, after this paper: background citation

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

TypeinterventionalSponsorUniversity Hospital, BonnRan2025 to 2029Enrolled130ConditionsParkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia DiseasesArmsIncrease of physical activity volume and intensity with the use of a motivational smartphone application
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Lifestyle medicine for neuroprotection: evidence and implementation in Asian contexts.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Article
  3. Article
  4. The epidemiology of Parkinson's disease.Lancet (London, England) · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Nienke M de VriesDonders Institute for Brain, Cognition and Behavior, Department of Neurology, Radboud University Medical Center, Nijmegen, the Netherlands.
Sirwan K L DarweeshDonders Institute for Brain, Cognition and Behavior, Department of Neurology, Radboud University Medical Center, Nijmegen, the Netherlands.
Bastiaan R BloemDonders Institute for Brain, Cognition and Behavior, Department of Neurology, Radboud University Medical Center, Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Parkinson DiseaseExerciseHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.