Evidence map›Paper›PMID 34724103›Full record

ArticleArchives of orthopaedic and trauma surgery2023

Do cobalt and chromium blood metal ion levels normalize after revision of failed metal-on-metal total hip replacements?

Anna Jungwirth-Weinberger, Carola Hanreich, Maximilian F Kasparek, Lisa Renner, Wenzel Waldstein, Friedrich Boettner

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Article in Archives of orthopaedic and trauma surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Tranexamic acid reduces blood loss in primary total hip arthroplasty performed using the direct anterior approach: a one-center retrospective observational study.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022
    Observational
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna Jungwirth-WeinbergerHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Carola HanreichHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Maximilian F KasparekEvangelisches Krankenhaus, Hans-Sachs-Gasse 10-12, 1180, Vienna, Austria.
Lisa RennerCharite, Chariteplatz 1, 10117, Berlin, Germany.
Wenzel WaldsteinAKH Wien, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Friedrich BoettnerHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA. boettnerf@hss.edu.ORCID http://orcid.org/0000-0002-7906-9486

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreased cobalt (Co) and chromium (Cr) serum levels are one reason for revision surgery in metal on metal (MoM) total hip arthroplasty (THA) patients. Dual mobility liners are a simple revision option; however, they preserve the metal shell and stem and it is therefore not clear if metal ion levels will fully normalize after revision surgery. MATERIAL AND

methodsBetween April 2013 and December 2017 25 hips (24 patients) underwent revision from a MoM THA to an off-label dual mobility liner. Five patients were lost to follow-up and one patient refused leaving 18 patients (11 men, 7 female, average age 63.9 years) for pre- and postoperative metal ion level blood tests at a minimum follow-up of 2 years.

resultsFourteen patients were revised for osteolysis, two for elevated metal ion levels and two for fluid or cysts around the femoral or acetabular component. The average preoperative Co and Cr levels were 8.3 µg/l and 5.0 µg/l, respectively. At a minimum follow-up of 2 years (30-95 months), metal ions dropped to 0.8 µg/l. Harris Hip Score (HHS), Hip Osteoarthritis Outcome Score (HOOS), Visual Analog Scale (VAS) and the UCLA activity score improved non-significantly from pre- to postoperative. There was one postoperative complication in the study cohort. One patient with persisting pain required revision surgery to a standard acetabular component during the follow-up period.

conclusionThe off-label use of a dual-mobility liner in the current study resulted in normalization of the metal ion levels suggesting that preserving the cobalt-chromium acetabular component has little impact on ion levels. In addition, dual mobility liners have a low complication and revision rate.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisMetal-on-Metal Joint ProsthesesChromiumCobaltFemaleFollow-Up StudiesHumansIonsMaleMetalsMiddle AgedProsthesis DesignReoperationChromiumCobaltIonsMetalsChromiumCobaltMetal-on-metalRevisionTotal hip arthroplasty

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.