SynthesisPloS one2021
The cost-effectiveness of physician assistants/associates: A systematic review of international evidence.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of Medical Associate Professions (MAPs) on the productivity, quality of care, patient and healthcare workforce satisfaction, and budget implications in various healthcare settings: a systematic review.BMC health services research · 2025Pooled it
- Physician associates and anaesthetic associates in UK: rapid systematic review of recent UK based research.BMJ (Clinical research ed.) · 2025Pooled it
- How Government Policies and Organisational and Sectoral Circumstances Influence Nurse Practitioner and Physician Assistant Employment and Training: A Realist Analysis Using Surveys.Journal of advanced nursing · 2026Article
- Physician Assistants in Australia. Function and Friction in Australian Healthcare: An Integrative Review.The Australian journal of rural health · 2026Review
- Review
- Review
- Motivations of Israeli physicians to return, or not, to Israel after their fellowship abroad.Israel journal of health policy research · 2024Article
- Article
- Strategy amidst complexity-what lies ahead for Indian healthcare.The Lancet regional health. Southeast Asia · 2023Article
- Flexner has fallen: Transitions in medical education system across time, a gradual return to pre-Flexnerian state (de-Flexnerization).World journal of clinical cases · 2023Review
- The influence of government policies on the nurse practitioner and physician assistant workforce in the Netherlands, 2000-2022: a multimethod approach study.BMC health services research · 2023Review
- Evaluation of the impact of technical physicians on improving individual patient care with technology.BMC medical education · 2023Article
- The main features of physician assistants/associates and insights for the development of similar professions in China.Journal of evidence-based medicine · 2022Review
- Stakeholders' views on the utility and employment strategies of clinical associates.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- Gender disparity regarding work-life balance satisfaction among German neuro-oncologists: a YoungNOA survey.Neuro-oncology · 2022Article
- Forecasting the physician assistant/associate workforce: 2020-2035.Future healthcare journal · 2022Article
- Increased reliance on physician assistants: an access-quality tradeoff?Journal of market access & health policy · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe global utilization of the physician assistant/associate (PA) is growing. Their increasing presence is in response to the rising demands of demographic changes, new developments in healthcare, and physician shortages. While PAs are present on four continents, the evidence of whether their employment contributes to more efficient healthcare has not been assessed in the aggregate. We undertook a systematic review of the literature on PA cost-effectiveness as compared to physicians. Cost-effectiveness was operationalized as quality, accessibility, and the cost of care. METHODS AND
findingsLiterature to June 2021 was searched across five biomedical databases and filtered for eligibility. Publications that met the inclusion criteria were categorized by date, country, design, and results by three researchers independently. All studies were screened with the Risk of Bias in Non-randomised Studies-of Interventions (ROBIN-I) tool. The literature search produced 4,855 titles, and after applying criteria, 39 studies met inclusion (34 North America, 4 Europe, 1 Africa). Ten studies had a prospective design, and 29 were retrospective. Four studies were assessed as biased in results reporting. While most studies included a small number of PAs, five studies were national in origin and assessed the employment of a few hundred PAs and their care of thousands of patients. In 34 studies, the PA was employed as a substitute for traditional physician services, and in five studies, the PA was employed in a complementary role. The quality of care delivered by a PA was comparable to a physician's care in 15 studies, and in 18 studies, the quality of care exceeded that of a physician. In total, 29 studies showed that both labor and resource costs were lower when the PA delivered the care than when the physician delivered the care.
conclusionsMost of the studies were of good methodological quality, and the results point in the same direction; PAs delivered the same or better care outcomes as physicians with the same or less cost of care. Sometimes this efficiency was due to their reduced labor cost and sometimes because they were more effective as producers of care and activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.