SynthesisPloS one2021
The burden of stroke and modifiable risk factors in Ethiopia: A systemic review and meta-analysis.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Treatment outcomes and associated factors of stroke in Ethiopia: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Epidemiology and clinical implications of atrial fibrillation among stroke patients in Ethiopia: a comprehensive systematic review and meta-analysis.BMC neurology · 2024Pooled it
- Knowledge and Practice Regarding Stroke Prevention and Associated Factors Among Hypertensive Patients at Selected Public Hospitals in Addis Ababa, Ethiopia: A Cross-Sectional Study.Health science reports · 2026Article
- Post-Stroke Limitations on Activities of Daily Living and Associated Factors in Public Tertiary Hospitals in Amhara Regional State, Ethiopia: A Multicenter Cross-Sectional Study.Health science reports · 2026Article
- Posttraumatic stress disorder and associated factors among stroke survivors in Northwest Ethiopia.Discover mental health · 2025Article
- Knowledge, attitude, and practice of stroke and its risk factors and warning symptoms in Ethiopia.BMC neurology · 2025Article
- Post stroke fall and associated factors among stroke survivors at hospitals in Jimma town, oromia regional state, Southwest Ethiopia, 2025: a cross sectional study.BMC neurology · 2025Article
- Demographic Disparities in Stroke Occurrence: Insights From an Integrative Review of Emerging Trends.Brain and behavior · 2025Review
- AdaptRehab VR: Development of an Immersive Virtual Reality System for Upper Limb Stroke Rehabilitation Designed for Low- and Middle-Income Countries Using a Participatory Co-Creation Approach.Bioengineering (Basel, Switzerland) · 2025Article
- Predictors of pre-hospital delay among stroke patients in Yekatit-12 hospital Addis Ababa, Ethiopia: unmatched case-control study.International journal of emergency medicine · 2025Article
- Article
- 30-day in-hospital stroke case fatality and significant risk factors in sub-Saharan-Africa: A systematic review and meta-analysis.PLOS global public health · 2024Article
- Determinants of stroke among adult hypertensive patients on follow up in Addis Ababa public hospitals, Ethiopia: A case control study.PloS one · 2024Article
- Diabetes Mellitus as a risk factor for stroke among Nigerians: A systematic review and meta-analysis.International journal of cardiology. Cardiovascular risk and prevention · 2023Review
- Knowledge of stroke risk factors and warning symptoms among adults with type 2 diabetes in Addis Ababa, Ethiopia, 2021: an institution-Based cross-sectional study.BMC cardiovascular disorders · 2023Article
- Poor treatment outcomes and associated factors among hospitalized patients with stroke at Hiwot Fana Comprehensive Specialized Hospital, eastern Ethiopia.Frontiers in stroke · 2023Article
- Survival status and predictors of mortality among adult Stroke patients admitted to Jimma University Medical Center, South west Ethiopia: A retrospective Cohort study.Vascular health and risk management · 2023Article
- The prevalence of stroke among adults in Ethiopia from 2012 to 2022: A systematic review and meta-analysis protocol.PloS one · 2023Article
- Angiotensin-converting enzyme gene insertion/deletion polymorphism and risk of ischemic stroke complication among patients with hypertension in the Ethiopian population.Frontiers in neurology · 2023Article
- Cause-Specific Mortality Fraction (CSMF) of adult mortality in Butajira, South Central Ethiopia.PLOS global public health · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe burden and contribution of modifiable risk factors of stroke in Ethiopia are unclear. Knowledge about this burden and modifying risk factors is pivotal for establishing stroke prevention strategies. In recent decades, the issue of lifestyle and behavioral modification is a key to improve the quality of life. The modifiable risk factors are an importance as intervention strategies aimed at reducing these factors can subsequently reduce the risk of stroke. So far, many primary studies were conducted to estimate the burden of stroke and modifiable risk factors in Ethiopia. However, the lack of a nationwide study that determines the overall pooled estimation of burden and modifiable risk factors of stroke is a research gap.
methodsTo conduct this systemic review and meta-analysis, we are following the PRISMA checklist. Three authors searched and extracted the data from the CINAHL (EBSCO), MEDLINE (via Ovid), PubMed, EMcare, African Journals Online (AJOL), and Google scholar. The quality of the primary study was assessed using the Newcastle-Ottawa Scale (NOS) by two independent reviewers. The primary studies with low and moderate risk of bias were included in the final analysis. The authors presented the pooled estimated burden of stroke and its modifiable risk factors. The registered protocol number in PROSPERO was CRD42020221906.
resultsIn this study, the pooled burden of hemorrhagic and ischemic stroke were 46.42% (95%CI: 41.82-51.53; I2 = 91.6%) and 51.40% (95%CI: 46.97-55.82; I2 = 85.5%) respectively. The overall magnitude of modifiable risk factor of hypertension, alcohol consumption and dyslipidemia among stroke patients were 49% (95%CI: 43.59, 54.41), 24.96% (95CI%:15.01, 34.90), and 20.99% (95%CI: 11.10, 30.88), respectively. The least proportion of stroke recovery was in the Oromia region (67.38 (95%CI: 41.60-93.17; I2 = 98.1%). Farther more, the proportion of stroke recovery was decreased after 2017 (70.50 (56.80-84.20).
conclusionsIn our study, more than 90% of stroke patients had one or more modifiable risk factors. All identified modifiable stroke risk factors are major public health issues in Ethiopia. Therefore, strategy is designed for stroke prevention to decrease stroke burden through targeted modification of a single risk factor, or a cluster of multiple risk factors, used on a population, community, or individual level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.