Evidence map›Paper›PMID 34723510›Full record

ArticleACS synthetic biology2021

CRISPR-Cas-Mediated Tethering Recruits the Yeast

Emily R Cliff, Robin L Kirkpatrick, Daniel Cunningham-Bryant, Brianna Fernandez, Joseph L Harman, Jesse G Zalatan

Abstract read
In one paragraph

Article in ACS synthetic biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily R Cliff
Robin L Kirkpatrick
Daniel Cunningham-Bryant
Brianna Fernandez
Joseph L Harman

Funding

INTERDISCIPLINARY TRAINING IN GENOMIC SCIENCEST32HG000035 · NHGRI · UNIVERSITY OF WASHINGTON · PI Bruce Colston Trapnell · 1995 to 2026
$24.2M
Spatial Organization in Biochemical Reaction NetworksR35GM124773 · NIGMS · UNIVERSITY OF WASHINGTON · PI Jesse George Zalatan · 2017 to 2026
$3.9M
NHGRI NIH HHS T32 HG000035NIGMS NIH HHS R35 GM124773
6 · The paper itself

Abstract

To investigate the relationship between genome structure and function, we have developed a programmable CRISPR-Cas system for nuclear peripheral recruitment in yeast. We benchmarked this system at the

Indexed as

Cell NucleusCRISPR-Cas SystemsDNA-Binding ProteinsGene ExpressionGene SilencingGenes, ReporterGenetic TechniquesGenome, BacterialSaccharomyces cerevisiaeDNA-Binding ProteinsCRISPR-CasdCas9gene silencinggenome structureHMRnuclear periphery

Identifiers

PMID34723510
PMCPMC8627703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.