Evidence map›Paper›PMID 34723320›Full record

ArticleNucleic acids research2022

ViRBase v3.0: a virus and host ncRNA-associated interaction repository with increased coverage and annotation.

Jun Cheng, Yunqing Lin, Linfu Xu, Kechen Chen, Qi Li, Kaixin Xu, Lin Ning, Juanjuan Kang, Tianyu Cui, Yan Huang and 5 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Computational Analysis of Virus-Host Interactomes.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Hepatitis B Virus and microRNAs: A Bioinformatics Approach.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jun ChengAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University (Foshan Maternity & Child Healthcare Hospital), Foshan 528000, China.
Yunqing LinCenter for Cell Lineage and Atlas (CCLA), Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou 510005, China.
Linfu XuDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Kechen ChenDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Qi LiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Kaixin XuDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Lin NingDermatology Hospital, Southern Medical University, Guangzhou 510091, China.
Juanjuan KangAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University (Foshan Maternity & Child Healthcare Hospital), Foshan 528000, China.
Tianyu CuiDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yan HuangDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Xiaoyang ZhaoState Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Dong WangDepartment of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0003-0988-7405
Yanhui LiInstitute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University Health Science Center, Beijing, PR China.
Xi SuAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University (Foshan Maternity & Child Healthcare Hospital), Foshan 528000, China.
Bin YangDermatology Hospital, Southern Medical University, Guangzhou 510091, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a means to aid in the investigation of viral infection mechanisms and identification of more effective antivirus targets, the availability of a source which continually collects and updates information on the virus and host ncRNA-associated interaction resources is essential. Here, we update the ViRBase database to version 3.0 (http://www.virbase.org/ or http://www.rna-society.org/virbase/). This update represents a major revision: (i) the total number of interaction entries is now greater than 820,000, an approximately 70-fold increment, involving 116 virus and 36 host organisms, (ii) it supplements and provides more details on RNA annotations (including RNA editing, RNA localization and RNA modification), ncRNA SNP and ncRNA-drug related information and (iii) it provides two additional tools for predicting binding sites (IntaRNA and PRIdictor), a visual plug-in to display interactions and a website which is optimized for more practical and user-friendly operation. Overall, ViRBase v3.0 provides a more comprehensive resource for virus and host ncRNA-associated interactions enabling researchers a more effective means for investigation of viral infections.

Indexed as

Databases, GeneticGenome, ViralSoftwareBinding SitesChromatinHost-Pathogen InteractionsHumansInternetMolecular Sequence AnnotationPolymorphism, Single NucleotideRNA EditingRNA, UntranslatedSignal TransductionVirus DiseasesVirusesChromatinRNA, Untranslated

Identifiers

PMID34723320
PMCPMC8728225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.