Evidence map›Paper›PMID 34723261›Full record

ArticleJACS Au2021

Pnictogen-Bonding Catalysis and Transport Combined: Polyether Transporters Made In Situ.

Heorhii V Humeniuk, Andrea Gini, Xiaoyu Hao, Filipe Coelho, Naomi Sakai, Stefan Matile

Open access · goldAbstract read
In one paragraph

Article in JACS Au, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  6. Review
  7. Taxonomy of Chemical Bondings: Opportunities and Challenges.Angewandte Chemie (International ed. in English) · 2025
    Article
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  9. Article
  10. Article
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  12. Review
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  15. Are ArOrganometallics · 2023
    Article
  16. Article
  17. Anion-π catalysis on carbon allotropes.Beilstein journal of organic chemistry · 2023
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heorhii V HumeniukDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.
Andrea GiniDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.
Xiaoyu HaoDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.
Filipe CoelhoDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.
Naomi SakaiDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.ORCID https://orcid.org/0000-0002-9460-1944
Stefan MatileDepartment of Organic Chemistry, University of Geneva, 1211 Geneva, Switzerland.ORCID https://orcid.org/0000-0002-8537-8349
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of catalysis and transport across lipid bilayer membranes promises directional access to a solvent-free and structured nanospace that could accelerate, modulate, and, at best, enable new chemical reactions. To elaborate on these expectations, anion transport and catalysis with pnictogen and tetrel bonds are combined with polyether cascade cyclizations into bioinspired cation transporters. Characterized separately, synergistic anion and cation transporters of very high activity are identified. Combined for catalysis in membranes, cascade cyclizations are found to occur with a formal rate enhancement beyond one million compared to bulk solution and product formation is detected in situ as an increase in transport activity. With this operational system in place, intriguing perspectives open up to exploit all aspects of this unique nanospace for important chemical transformations.

Identifiers

PMID34723261
PMCPMC8549043
OpenAlexW3204501668

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.