ReviewJACS Au2021
Where Biology and Traditional Polymers Meet: The Potential of Associating Sequence-Defined Polymers for Materials Science.
Review in JACS Au, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Sequence-Controlled Copolymers Through Selective Ring-Opening Polymerization of Multiunit Macrolactones.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Sequence-defined polymers for predictable gene delivery.Nature reviews. Chemistry · 2026Review
- Thermodynamic Frontiers in Hemoglobin-Inspired Polymer Science for Diagnosis and Modulation of Neurodegenerative Diseases.Cell biochemistry and function · 2026Review
- Stereocontrol as a tool for shaping abiotic, sequence-defined oligourethanes.Polymer chemistry · 2026Article
- Customizing Ionic Micelles by Dynamic Coassembly of Sequence-Defined Peptoid Block Copolymers.Macromolecules · 2026Article
- Self-driving lab for the data-driven design of single-chain polymer nanoparticles.Cell press blue · 2026Article
- Sequence-Structure-Property Relationships in Short-Chain Polyesters: How Primary Structure Governs Macroscopic Performance.Macromolecules · 2026Article
- Synergizing Chemical and AI Communities for Advancing Laboratories of the Future.ACS central science · 2026Review
- Learning nature's assembly language with polymers.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Ultrasound-Triggered Self-Assembly of Discrete Oligourethanes into Supramolecular Gels: Importance of Stereocenter Sequence.ACS macro letters · 2026Article
- Computational design of functional random heteropolymers through atomistic simulations.PloS one · 2026Article
- Seed Oligomers Regulate Sequence Development through a Templating Effect in Simulated Irreversible Step-Growth Copolymerization.Macromolecules · 2025Article
- Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Seeking Precise Protein-like Functions from Random Heteropolymer Ensemble and through Dimensionality Reduction.ACS central science · 2025Review
- Molecular Weight Control in Frontal Ring-Opening Metathesis Polymerization.Angewandte Chemie (International ed. in English) · 2025Article
- Efficient Solution-Phase Synthesis of Sequence-Defined Oligourethanes with Precise Chirality Control.Macromolecular rapid communications · 2025Article
- Sequence-defined peptoidsChemical science · 2025Article
- Modulating the Aqueous Micellar Reorganization of Sequence-Defined Ionic Peptoid Block Copolymers by Ionizable Monomer Position and Solution pH.Macromolecules · 2025Article
- Sequence-Sensitivity in Functional Synthetic Polymer Properties.Angewandte Chemie (International ed. in English) · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polymers with precisely defined monomeric sequences present an exquisite tool for controlling material properties by harnessing both the robustness of synthetic polymers and the ability to tailor the inter- and intramolecular interactions so crucial to many biological materials. While polymer scientists traditionally synthesized and studied the physics of long molecules best described by their statistical nature, many biological polymers derive their highly tailored functions from precisely controlled sequences. Therefore, significant effort has been applied toward developing new methods of synthesizing, characterizing, and understanding the physics of non-natural sequence-defined polymers. This perspective considers the synergistic advantages that can be achieved via tailoring both precise sequence control and attributes of traditional polymers in a single system. Here, we focus on the potential of sequence-defined polymers in highly associating systems, with a focus on the unique properties, such as enhanced proton conductivity, that can be attained by incorporating sequence. In particular, we examine these materials as key model systems for studying previously unresolvable questions in polymer physics including the role of chain shape near interfaces and how to tailor compatibilization between dissimilar polymer blocks. Finally, we discuss the critical challenges-in particular, truly scalable synthetic approaches, characterization and modeling tools, and robust control and understanding of assembly pathways-that must be overcome for sequence-defined polymers to attain their potential and achieve ubiquity.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.