ArticleGlomerular diseases2021
Racial-ethnic differences in health-related quality of life among adults and children with glomerular disease.
Article in Glomerular diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026Review
- New Index Demonstrates Association between Social Vulnerability, Environmental Burden, and Kidney Failure Risk among Individuals with Glomerular Disease.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Systematic decision frameworks for the socially responsible use of precision medicine.NPJ genomic medicine · 2024Article
- Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression.Kidney international reports · 2024Article
- Association of mental health-related patient reported outcomes with blood pressure in adults and children with primary proteinuric glomerulopathies.Journal of nephrology · 2024Observational
- Psychosocial supports within pediatric nephrology practices: A pediatric nephrology research consortium survey.PloS one · 2023Article
- Immunosuppression Exposure and Risk of Infection-Related Acute Care Events in Patients With Glomerular Disease: An Observational Cohort Study.Kidney medicine · 2022Article
- Ridge Regression for Functional Form Identification of Continuous Predictors of Clinical Outcomes in Glomerular Disease.Glomerular diseasesArticle
- CureGN-Diabetes Study: Rationale, Design, and Methods of a Prospective Observational Study of Glomerular Disease Patients with Diabetes.Glomerular diseasesArticle
- Acute Care Visits and Subsequent Health-Related Quality of Life among Children and Adults with Glomerular Disease in the Cure Glomerulonephropathy Cohort.Glomerular diseasesArticle
Corrections and comments
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Authors and funding
27 authors at 20 institutions in 3 countries.
Funding
Abstract
introductionDisparities in health-related quality of life (HRQOL) have been inadequately studied in patients with glomerular disease. The aim of this study was to identify relationships between race/ethnicity, socioeconomic status, disease severity, and HRQOL in an ethnically and racially diverse cohort of patients with glomerular disease.
methodsCure Glomerulonephropathy (CureGN) is a multinational cohort study of patients with biopsy-proven glomerular disease. Associations between race/ethnicity and HRQOL were determined by the following: 1. Missed school or work due to kidney disease; 2. Responses to Patient Reported Outcomes Measurement Information System (PROMIS) questionnaires. We adjusted for demographics, socioeconomic status, and disease characteristics using multivariable logistic and linear regression.
resultsBlack and Hispanic participants had worse socioeconomic status and more severe glomerular disease than White or Asian participants. Black adults missed work or school most frequently due to kidney disease (30% versus 16-23% in the other three groups, p=0.04), and had the worst self-reported global physical health (median score 44.1 versus 48.0-48.2, p<0.001) and fatigue (53.8 versus 48.5-51.1, p=0.002), compared to other racial/ethnic groups. However, these findings were not statistically significant with adjustment for socioeconomic status and disease severity, both of which were strongly associated with HRQOL in adults. Among children, disease severity but not race/ethnicity or socioeconomic status were associated with HRQOL.
conclusionsAmong patients with glomerular disease enrolled in CureGN, the worse HRQOL reported by Black adults was attributable to lower socioeconomic status and more severe glomerular disease. No racial/ethnic differences in HRQOL were observed in children.
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