Evidence map›Paper›PMID 34723228›Full record

ArticleThe Lancet. Microbe2022

Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort study in Uganda.

Jane Achan, Asadu Serwanga, Humphrey Wanzira, Tonny Kyagulanyi, Anthony Nuwa, Godfrey Magumba, Stephen Kusasira, Isaac Sewanyana, Kevin Tetteh, Chris Drakeley and 7 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet. Microbe, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
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  6. Circulation of SARS-CoV-2 and Co-Infection withInfectious disease reports · 2025
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  8. Review
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  18. Review
  19. Article
  20. Exploring SARS-CoV-2 andFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Jane AchanGlobal Technical Team, Malaria Consortium, London, UK.
Asadu SerwangaTechnical Department, Malaria Consortium, Kampala, Uganda.
Humphrey WanziraTechnical Department, Malaria Consortium, Kampala, Uganda.
Tonny KyagulanyiTechnical Department, Malaria Consortium, Kampala, Uganda.
Anthony NuwaTechnical Department, Malaria Consortium, Kampala, Uganda.
Godfrey MagumbaTechnical Department, Malaria Consortium, Kampala, Uganda.
Stephen KusasiraDirectorate of Health, Ministry of Defense, Kampala, Uganda.
Isaac SewanyanaCentral Public Health Laboratories, Ministry of Health, Kampala, Uganda.
Kevin TettehFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Chris DrakeleyFaculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Fredrick NakwagalaDepartment of Medicine, Mulago Specialist Referral Hospital, Kampala, Uganda.
Helen AanyuDepartment of Paediatrics and Child Health, Mulago Specialist Referral Hospital, Kampala, Uganda.
Jimmy OpigoNational Malaria Control Division, Ministry of Health, Kampala, Uganda.
Prudence HamadeGlobal Technical Team, Malaria Consortium, London, UK.
Madeleine MarasciuloGlobal Technical Team, Malaria Consortium, Raleigh, NC, USA.
Byarugaba BateranaDepartment of Medicine, Mulago Specialist Referral Hospital, Kampala, Uganda.
James K TibenderanaGlobal Technical Team, Malaria Consortium, London, UK.
Malaria Consortium · UGMalaria Consortium · GBMinistry of Health · UGMulago Hospital · UGLondon School of Hygiene & Tropical Medicine · GBMalaria Consortium · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential effects of SARS-CoV-2 and

methodsThis was an exploratory prospective, cohort study of patients with COVID-19 who were admitted to hospital in Uganda. Patients of all ages with a PCR-confirmed diagnosis of SARS-CoV-2 infection who had provided informed consent or assent were consecutively enrolled from treatment centres in eight hospitals across the country and followed up until discharge or death. Clinical assessments and blood sampling were done at admission for all patients. Malaria diagnosis in all patients was done by rapid diagnostic tests, microscopy, and molecular methods. Previous

findingsOf 600 people with PCR-confirmed SARS-CoV-2 infection enrolled from April 15, to Oct 30, 2020, 597 (>99%) had complete information and were included in our analyses. The majority (502 [84%] of 597) were male individuals with a median age of 36 years (IQR 28-47). Overall prevalence of

interpretationAlthough patients with COVID-19 with

fundingMalaria Consortium (USA).

Indexed as

CoinfectionCOVID-19MalariaMalaria, FalciparumAdolescentAdultChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMaleMiddle AgedProspective Studies

Identifiers

PMID34723228
PMCPMC8545833
OpenAlexW3209674504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.