Evidence map›Paper›PMID 34722963›Full record

ArticleACS omega2021

Mechanism of Action of

Misgina B Girma, Haley S Ball, Xu Wang, Robert C Brothers, Emily R Jackson, Marvin J Meyers, Cynthia S Dowd, Robin D Couch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Misgina B GirmaDepartment of Chemistry and Biochemistry, George Mason University, Manassas, Virginia 20110, United States.ORCID https://orcid.org/0000-0002-5510-0514
Haley S BallDepartment of Chemistry and Biochemistry, George Mason University, Manassas, Virginia 20110, United States.
Xu WangProgenra Inc., Malvern, Pennsylvania 19355, United States.ORCID https://orcid.org/0000-0001-7379-5789
Robert C BrothersDepartment of Chemistry, The George Washington University, Washington, District of Columbia 20052, United States.
Emily R JacksonDepartment of Chemistry, The George Washington University, Washington, District of Columbia 20052, United States.
Marvin J MeyersDepartment of Chemistry, Saint Louis University, Saint Louis, Missouri 63103, United States.
Cynthia S DowdDepartment of Chemistry, The George Washington University, Washington, District of Columbia 20052, United States.
Robin D CouchDepartment of Chemistry and Biochemistry, George Mason University, Manassas, Virginia 20110, United States.
George Mason University · USGeorge Washington University · USProgenra (United States) · USSaint Louis University · US

Funding

Inhibition of MEP pathway Isoprenoid BiosynthesisR01AI123433 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI DOWD, CYNTHIA SCHIECK, MEYERS, MARVIN J · 2016 to 2020
$2.6M
NIAID NIH HHS R01 AI123433
6 · The paper itself

Abstract

Malaria is a global health threat that requires immediate attention. Malaria is caused by the protozoan parasite

Identifiers

PMID34722963
PMCPMC8552233
OpenAlexW3206681658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.