Evidence map›Paper›PMID 34722896›Full record

ArticleOpen medicine (Warsaw, Poland)2021

High quality of 58-month life in lung cancer patient with brain metastases sequentially treated with gefitinib and osimertinib.

Ying Zhang, Xiaowen Zhang, Fang Wang, Yan Feng, Huaping Tang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Open medicine (Warsaw, Poland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ying ZhangDepartment of Respiration Medicine, Qingdao Municipal Hospital, Qingdao, China.
Xiaowen ZhangDepartment of Traditional Chinese Acupuncture and Manipulation, Shandong University of Traditional Chinese Medicine, Jinan, China.
Fang WangDepartment of Respiration Medicine, Qingdao Municipal Hospital, Qingdao, China.
Yan FengDepartment of Respiration Medicine, Qingdao Municipal Hospital, Qingdao, China.
Huaping TangDepartment of Respiration Medicine, Qingdao Municipal Hospital, Qingdao, China.
Qingdao Municipal Hospital · CNQingdao University · CNShandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain metastases (BMs) and bone metastases seriously affect the prognosis of lung cancer patients. How to optimize the use of existing targeted drugs is an important way to address the clinical needs of the central nervous system in the individualized treatment of non-small cell lung cancer (NSCLC). In this report, we describe an NSCLC patient with BMs who survived for 58 months, which is the longest survival case among lung cancer patients with BMs. The patient was initially diagnosed with lung cancer more than 5 years ago with simultaneous brain, bone, and lung metastases. After gefitinib resistance, she received osimertinib in sequence with no progress for 58 months in total and maintained very good quality of life.

Indexed as

bone metastasisbrain metastasesexon 21 mutationgefitiniblung adenocarcinoma cancerosimertinibT790M mutation

Identifiers

PMID34722896
PMCPMC8546288
OpenAlexW3208330346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.