Evidence map›Paper›PMID 34722812›Full record

ArticleInternational journal of particle therapy2021

Assessment of Knowledge-Based Planning for Prostate Intensity Modulated Proton Therapy.

Yihang Xu, Nellie Brovold, Jonathan Cyriac, Elizabeth Bossart, Kyle Padgett, Michael Butkus, Tejan Diwanj, Adam King, Alan Dal Pra, Matt Abramowitz and 2 more

Open access · diamondAbstract read
In one paragraph

Article in International journal of particle therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Three-dimensional dose and LETMedical physics · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yihang XuDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Nellie BrovoldDepartment of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA.
Jonathan CyriacDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Elizabeth BossartDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Kyle PadgettDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Michael ButkusDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Tejan DiwanjDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Adam KingDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Alan Dal PraDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Matt AbramowitzDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Alan PollackDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
Nesrin DoganDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
University of Miami · USHenry Ford Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the performance of a proton-specific knowledge based planning (KBPP) model in creation of robustly optimized intensity-modulated proton therapy (IMPT) plans for treatment of patients with prostate cancer. MATERIALS AND

methodsForty-five patients with localized prostate cancer, who had previously been treated with volumetric modulated arc therapy, were selected and replanned with robustly optimized IMPT. A KBPP model was generated from the results of 30 of the patients, and the remaining 15 patient results were used for validation. The KBPP model quality and accuracy were evaluated with the model-provided organ-at-risk regression plots and metrics. The KBPP quality was also assessed through comparison of expert and KBPP-generated IMPT plans for target coverage and organ-at-risk sparing.

resultsThe resulting

conclusionsThe results demonstrated that robustly optimized IMPT plans created by the KBPP model are of high quality and are comparable to expert plans. Furthermore, the KBPP model can generate more-robust and more-homogenous plans compared with those of expert plans. More studies need to be done for the validation of the proton KBPP model at more-complicated treatment sites.

Indexed as

IMPTknowledge-based planningprostate cancer

Identifiers

PMID34722812
PMCPMC8489488
OpenAlexW3170789064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.