Evidence map›Paper›PMID 34722807›Full record

ArticleInternational journal of particle therapy2021

Consensus Statement on Proton Therapy for Prostate Cancer.

Curtis M Bryant, Randal H Henderson, R Charles Nichols, William M Mendenhall, Bradford S Hoppe, Carlos E Vargas, Thomas B Daniels, C Richard Choo, Rahul R Parikh, Huan Giap and 9 more

Abstract read
In one paragraph

Article in International journal of particle therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Towards proton therapy guidelines for radiation therapists and dosimetrists: A scoping review.Technical innovations & patient support in radiation oncology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. 3DPhysics in medicine and biology · 2022
    Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Curtis M BryantDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Randal H HendersonDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
R Charles NicholsDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
William M MendenhallDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Bradford S HoppeDepartment of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA.
Carlos E VargasDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
Thomas B DanielsDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA.
C Richard ChooDepartment of Radiation Oncology, Mayo Clinic Rochester, Rochester, MN, USA.
Rahul R ParikhDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
Huan GiapDepartment of Radiation Oncology, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, USA.
Jerry D SlaterDepartment of Radiation Oncology, Loma Linda University, Loma Linda, CA, USA.
Neha VapiwalaDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
William BarrettDepartment of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USA.
Akash NandaDepartment of Radiation Oncology, Orlando Health, Orlando, FL, USA.
Mark V MishraDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
Seungtaek ChoiDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA.
Jay J LiaoDepartment of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USA.
Nancy P MendenhallDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Genitourinary Subcommittee of the Particle Therapy Co-Operative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.

Indexed as

particle therapyprostate cancerproton therapyradiation therapy

Identifiers

PMID34722807
PMCPMC8489490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.