Evidence map›Paper›PMID 34722719›Full record

ReviewVisceral medicine2021

Current Endoscopic Resection Techniques for Gastrointestinal Lesions: Endoscopic Mucosal Resection, Submucosal Dissection, and Full-Thickness Resection.

Arthur Hoffman, Raja Atreya, Timo Rath, Markus Ferdinand Neurath

Open access · bronzeAbstract readReview
In one paragraph

Review in Visceral medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Quality indicators for upper GI endoscopy.Gastrointestinal endoscopy · 2025
    Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Quality Indicators for Upper GI Endoscopy.The American journal of gastroenterology · 2025
    Article
  8. Article
  9. Risk Factors of Gastrointestinal Perforation with a Poor Prognosis.International journal of general medicine · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Arthur HoffmanDepartment of Internal Medicine III, Aschaffenburg-Alzenau Clinic, Aschaffenburg, Germany.
Raja AtreyaFirst Department of Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Timo RathFirst Department of Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Markus Ferdinand NeurathFirst Department of Medicine, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEKlinikum Aschaffenburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic resection of dysplastic lesions in early stages of cancer reduces mortality rates and is recommended by many national guidelines throughout the world. Snare polypectomy and endoscopic mucosal resection (EMR) are established techniques of polyp removal. The advantages of these methods are their relatively short procedure times and acceptable complication rates. The latter include delayed bleeding in 0.9% and a perforation risk of 0.4-1.3%, depending on the size and location of the resected lesion. EMR is a recent modification of endoscopic resection. A limited number of studies suggest that larger lesions can be removed en bloc with low complication rates and short procedure times. Novel techniques such as endoscopic submucosal dissection (ESD) are used to enhance en bloc resection rates for larger, flat, or sessile lesions. Endoscopic full-thickness resection (EFTR) is employed for non-lifting lesions or those not easily amenable to resection. Procedures such as ESD or EFTR are emerging standards for lesions inaccessible to EMR techniques. SUMMARY: Endoscopic treatment is now regarded as first-line therapy for benign lesions. KEY MESSAGE: Endoscopic resection of dysplastic lesions or early stages of cancer is recommended. A plethora of different techniques can be used dependent on the lesions.

Indexed as

Complication ratesEarly cancerEndoscopic resectionResection techniques

Identifiers

PMID34722719
PMCPMC8543363
OpenAlexW3148224986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.