Evidence map›Paper›PMID 34722666›Full record

ArticleFrontiers in cardiovascular medicine2021

Acute Stent-Induced Endothelial Denudation: Biomechanical Predictors of Vascular Injury.

Claire Conway, Farhad R Nezami, Campbell Rogers, Adam Groothuis, James C Squire, Elazer R Edelman

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claire ConwayDepartment of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Farhad R NezamiInstitute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, United States.
Campbell RogersInstitute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, United States.
Adam GroothuisInstitute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, United States.
James C SquireDepartment of Electrical and Computer Engineering, Virginia Military Institute, Lexington City, KY, United States.
Elazer R EdelmanInstitute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent concern for local drug delivery and withdrawal of the first Food and Drug Administration-approved bioresorbable scaffold emphasizes the need to optimize the relationships between stent design and drug release with imposed arterial injury and observed pharmacodynamics. In this study, we examine the hypothesis that vascular injury is predictable from stent design and that the expanding force of stent deployment results in increased circumferential stress in the arterial tissue, which may explain acute injury poststent deployment. Using both numerical simulations and

Indexed as

computational fluid dynamicscoronary arteryendothelial injuryendovascular stentfinite element analysis

Identifiers

PMID34722666
PMCPMC8553954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.